Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.53 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAN1B1 | Q9UKM7 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9112636 | 0.79 | ALDH1A1 (0.40) | MEN1KMT2ATDP1 | |
| SCHEMBL23023143 | 0.73 | TDP1 (0.47) | HTR2CMEN1KMT2ATDP1 | |
| SCHEMBL2019717 | 0.72 | HTR2C (0.64) | HTR2CCXCR4HTR2AMEN1KMT2A | |
| SCHEMBL2019718 | 0.72 | HTR2C (0.64) | HTR2CCXCR4HTR2AMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL4523862 | 0.70 | HTR2C (0.62) | HTR2CCXCR4HTR2AMEN1KMT2A | |
| SCHEMBL23022863 | 0.70 | HTR2C (0.57) | HTR2CCXCR4HTR2AMEN1KMT2A | |
| SCHEMBL4137817 | 0.69 | HTR2C (1.00) | HTR2CHTR2AMEN1KMT2ATDP1 | |
| SCHEMBL4137819 | 0.69 | HTR2C (1.00) | HTR2CHTR2AMEN1KMT2ATDP1 | |
| SCHEMBL2934330 | 0.69 | CXCR4 (0.69) | HTR2CCXCR4HTR2AMEN1KMT2A | |
| SCHEMBL16083006 | 0.69 | CXCR4 (0.69) | HTR2CCXCR4HTR2AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210053997-A1 | TRNA SYNTHETASE INHIBITORS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2021-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210053997-A1 | TRNA SYNTHETASE INHIBITORS | TRMT1, AARS1, GARS1 | HTR2C 4102/4885CXCR4 4760/4885HTR2A 3576/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.