Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HMGCR | P04035 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19038877 | 0.87 | CTSA (0.40) | CTSAACHEALDH1A1L3MBTL1HMGCR | |
| SCHEMBL29159410 | 0.85 | CTSA (0.39) | CTSAACHEALDH1A1L3MBTL1HMGCR | |
| SCHEMBL4895468 | 0.78 | CTSA (0.42) | CTSAACHEALDH1A1L3MBTL1HMGCR | |
| SCHEMBL29868598 | 0.74 | CTSA (0.57) | CTSAACHEALDH1A1L3MBTL1HMGCR | |
| SCHEMBL9614591 | 0.74 | CTSA (0.43) | CTSAACHEALDH1A1L3MBTL1HMGCR | |
| SCHEMBL3437037 | 0.74 | CTSA (0.50) | CTSAACHEALDH1A1L3MBTL1HMGCR | |
| SCHEMBL10308654 | 0.74 | CTSA (0.43) | CTSAACHEALDH1A1L3MBTL1HMGCR | |
| SCHEMBL3975395 | 0.74 | CTSA (0.43) | CTSAACHEALDH1A1L3MBTL1KDM4E | |
| SCHEMBL11045983 | 0.74 | CTSA (0.39) | CTSAACHEALDH1A1L3MBTL1HMGCR | |
| SCHEMBL14111921 | 0.74 | CTSA (0.39) | CTSAACHEALDH1A1L3MBTL1HMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5359115-A | Reacting phosphonic monoester with dialkylazodicarboxylate, triphenylphosphine and secondary alcohol to form diester, hydrolyzing selective ester to form monoester, coupling an aminoacid to yield peptidylphosphonate | AFFYMAX TECHNOLOGIES, N.V. (US) | 1994-10-25 | — | — | US | claimed |
| US-20180179242-A1 | CATALYSTS AND METHODS FOR POLYMER SYNTHESIS | NOVOMER, INC. | 2018-06-28 | — | — | US | disclosed |
| US-9951096-B2 | Catalysts and methods for polymer synthesis | SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) | 2018-04-24 | — | — | US | disclosed |
| US-9856349-B2 | Catalysts and methods for polymer synthesis | SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) | 2018-01-02 | — | — | US | disclosed |
| US-20170183369-A1 | CATALYSTS AND METHODS FOR POLYMER SYNTHESIS | SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) | 2017-06-29 | — | — | US | disclosed |
| US-20170107241-A1 | SALEN COMPLEXES WITH DIANIONIC COUNTERIONS | NOVOMER, INC. (US) | 2017-04-20 | — | — | US | disclosed |
| US-20170080409-A1 | CATALYSTS FOR EPOXIDE CARBONYLATION | NOVOMER, INC. (US) | 2017-03-23 | — | — | US | disclosed |
| US-9505878-B2 | Catalysts and methods for polymer synthesis | NOVOMER, INC. (US) | 2016-11-29 | — | — | US | disclosed |
| US-9403861-B2 | Salen complexes with dianionic counterions | NOVOMER, INC. (US) | 2016-08-02 | — | — | US | disclosed |
| US-9394326-B2 | Catalysts and methods for polymer synthesis | NOVOMER, INC. (US) | 2016-07-19 | — | — | US | disclosed |
| US-20130172524-A1 | CATALYSTS AND METHODS FOR POLYMER SYNTHESIS | NOVOMER, INC. (US) | 2013-07-04 | — | — | US | disclosed |
| US-20130144032-A1 | CATALYSTS AND METHODS FOR POLYMER SYNTHESIS | NOVOMER, INC. (US) | 2013-06-06 | — | — | US | disclosed |
| US-20130144031-A1 | CATALYSTS AND METHODS FOR POLYMER SYNTHESIS | NOVOMER, INC. (US) | 2013-06-06 | — | — | US | disclosed |
| US-20130144033-A1 | CATALYSTS AND METHODS FOR POLYMER SYNTHESIS | NOVOMER, INC. (US) | 2013-06-06 | — | — | US | disclosed |
| US-20110152497-A1 | CATALYSTS AND METHODS FOR POLYMER SYNTHESIS | NOVOMER, INC. (US) | 2011-06-23 | — | — | US | disclosed |
| EP-0659188-A4 | METHODS FOR THE SYNTHESIS OF PHOSPHONATE ESTERS. | AFFYMAX TECH NV (AN) | 1995-11-22 | — | — | EP | disclosed |
| EP-0659188-A1 | METHODS FOR THE SYNTHESIS OF PHOSPHONATE ESTERS | AFFYMAX TECHNOLOGIES N.V. (AN) | 1995-06-28 | — | — | EP | disclosed |
| US-5420328-A | Esterification with alcohol and hydrolysis | AFFYMAX TECHNOLOGIES, N.V. (AN) | 1995-05-30 | — | — | US | disclosed |
| US-5359115-A | Reacting phosphonic monoester with dialkylazodicarboxylate, triphenylphosphine and secondary alcohol to form diester, hydrolyzing selective ester to form monoester, coupling an aminoacid to yield peptidylphosphonate | AFFYMAX TECHNOLOGIES, N.V. (US) | 1994-10-25 | — | — | US | disclosed |
| WO-1994006808-A1 | METHODS FOR THE SYNTHESIS OF PHOSPHONATE ESTERS | AFFYMAX TECHNOLOGIES N.V. (AN) | 1994-03-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170107241-A1 | SALEN COMPLEXES WITH DIANIONIC COUNTERIONS | NCLN, POLN, NCL | CTSA 3427/4885ACHE 2460/4885ALDH1A1 3519/4885 |
| US-20130144032-A1 | CATALYSTS AND METHODS FOR POLYMER SYNTHESIS | PPOX, COASY, SOD1 | CTSA 3327/4885ACHE 289/4885ALDH1A1 2255/4885 |
| US-20180179242-A1 | CATALYSTS AND METHODS FOR POLYMER SYNTHESIS | PPOX, COASY, SOD1 | CTSA 3327/4885ACHE 289/4885ALDH1A1 2255/4885 |
| US-20130144033-A1 | CATALYSTS AND METHODS FOR POLYMER SYNTHESIS | PPOX, COASY, SOD1 | CTSA 3327/4885ACHE 289/4885ALDH1A1 2255/4885 |
| US-20170183369-A1 | CATALYSTS AND METHODS FOR POLYMER SYNTHESIS | PPOX, COASY, SOD1 | CTSA 3327/4885ACHE 289/4885ALDH1A1 2255/4885 |
| US-20110152497-A1 | CATALYSTS AND METHODS FOR POLYMER SYNTHESIS | PPOX, COASY, SOD1 | CTSA 3327/4885ACHE 289/4885ALDH1A1 2255/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.