Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 3/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9113430 | 0.89 | EPHX2 (0.44) | EPHX2NR1H4MAOBMAOACYP1A1 | |
| SCHEMBL9111696 | 0.89 | EPHX2 (0.46) | EPHX2NR1H4MAOBMAOACYP1A1 | |
| SCHEMBL9112770 | 0.88 | EPHX2 (0.43) | EPHX2NR1H4MAOBMAOACYP1A1 | |
| SCHEMBL9112976 | 0.86 | EPHX2 (0.41) | EPHX2NR1H4MAOBMAOACYP1A1 | |
| SCHEMBL9113070 | 0.85 | POLB (0.41) | EPHX2NR1H4MAOBMAOACYP1A1 | |
| SCHEMBL9286479 | 0.83 | ACHE (0.39) | EPHX2NR1H4MAOBLMNAHPGD | |
| SCHEMBL9198798 | 0.74 | HDAC8 (0.40) | EPHX2NR1H4MAOBLMNAHPGD | |
| SCHEMBL9206463 | 0.71 | CACNA1B (0.39) | EPHX2NR1H4LMNAMAPK1HPGD | |
| SCHEMBL9202752 | 0.70 | HDAC8 (0.39) | EPHX2NR1H4MAOBLMNAHPGD | |
| SCHEMBL9998244 | 0.70 | TRPV1 (0.38) | NR1H4ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995006628-A1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES OR BACTERIA | STATENS SERUMINSTITUT (DK) | 1995-03-09 | — | — | WO | disclosed |