Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 4/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9202752 | 0.94 | HDAC8 (0.39) | HDAC8EPHX2NR1H4SMN1; SMN2ALDH1A1 | |
| SCHEMBL9198798 | 0.89 | HDAC8 (0.40) | HDAC8EPHX2NR1H4SMN1; SMN2ALDH1A1 | |
| SCHEMBL9113070 | 0.86 | POLB (0.41) | CACNA1BEPHX2NR1H4CYP2D6ALDH1A1 | |
| SCHEMBL9200646 | 0.86 | ELANE (0.39) | CYP2D6ELANESMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL9203802 | 0.84 | BCHE (0.41) | CYP2D6SMN1; SMN2ALDH1A1HPGDCYP3A4 | |
| SCHEMBL9202975 | 0.84 | CYP2D6 (0.39) | CACNA1BCYP2D6ELANESMN1; SMN2ALDH1A1 | |
| SCHEMBL9200541 | 0.83 | EPHX2 (0.41) | HDAC8EPHX2NR1H4SMN1; SMN2ALDH1A1 | |
| SCHEMBL9198805 | 0.82 | EPHX2 (0.38) | HDAC8EPHX2NR1H4SMN1; SMN2ALDH1A1 | |
| SCHEMBL9197566 | 0.82 | MAPT (0.35) | CACNA1BCYP2D6ELANESMN1; SMN2ALDH1A1 | |
| SCHEMBL9112976 | 0.81 | EPHX2 (0.41) | EPHX2NR1H4SMN1; SMN2ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0634927-A1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES, OR BACTERIA | STATENS SERUMINSTITUT (DK) | 1995-01-25 | — | — | EP | disclosed |
| WO-1993017671-A1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES, OR BACTERIA | STATENS SERUMINSTITUT (DK) | 1993-09-16 | — | — | WO | disclosed |