Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9113070 | 0.95 | POLB (0.41) | EPHX2NR1H4MAOBMAOACYP3A4 | |
| SCHEMBL9113430 | 0.92 | EPHX2 (0.44) | EPHX2NR1H4MAOBMAOAL3MBTL1 | |
| SCHEMBL9111696 | 0.88 | EPHX2 (0.46) | EPHX2NR1H4MAOBMAOAL3MBTL1 | |
| SCHEMBL9112770 | 0.87 | EPHX2 (0.43) | EPHX2NR1H4MAOBMAOAL3MBTL1 | |
| SCHEMBL9112841 | 0.86 | EPHX2 (0.42) | EPHX2NR1H4MAOBMAOAL3MBTL1 | |
| SCHEMBL9202752 | 0.85 | HDAC8 (0.39) | EPHX2NR1H4MAOBCYP3A4CYP2C9 | |
| SCHEMBL9206463 | 0.81 | CACNA1B (0.39) | EPHX2NR1H4CYP3A4CYP2C9LMNA | |
| SCHEMBL9198798 | 0.78 | HDAC8 (0.40) | EPHX2NR1H4MAOBLMNASMN1; SMN2 | |
| SCHEMBL27975595 | 0.71 | LMNA (0.57) | LMNASMN1; SMN2MAPTPOLBALDH1A1 | |
| SCHEMBL9200541 | 0.69 | EPHX2 (0.41) | EPHX2NR1H4MAOBLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995006628-A1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES OR BACTERIA | STATENS SERUMINSTITUT (DK) | 1995-03-09 | — | — | WO | disclosed |