Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | SCN4A | P35499 | 7/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | SCN1A | P35498 | 2/20 | 0.37 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.37 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.37 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.37 |
| ▸ | GBA1 | P04062 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13344106 | 0.85 | GABRA1 (0.43) | SCN8ATSHRSCN4ALMNASCN1A | |
| SCHEMBL27893818 | 0.81 | ALDH1A1 (0.38) | TSHRLMNACYP1A2SLC6A4SMN1; SMN2 | |
| SCHEMBL4513903 | 0.79 | SCN4A (0.41) | SCN8ATSHRSCN4ALMNASCN1A | |
| SCHEMBL11123175 | 0.79 | SCN8A (0.40) | SCN8ATSHRSCN4ALMNASCN1A | |
| SCHEMBL11088431 | 0.79 | SCN8A (0.40) | SCN8ATSHRSCN4ALMNASCN1A | |
| SCHEMBL24378512 | 0.79 | SCN8A (0.40) | SCN8ATSHRSCN4ALMNASCN1A | |
| SCHEMBL4895058 | 0.79 | SCN4A (0.43) | SCN8ATSHRSCN4ALMNASCN1A | |
| SCHEMBL95872 | 0.79 | CA12 (0.53) | TSHRLMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4897798 | 0.79 | PDCD1 (0.41) | SCN8ATSHRSCN4ALMNASCN1A | |
| SCHEMBL4094425 | 0.79 | SCN8A (0.37) | SCN8ATSHRSCN4ALMNASCN1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1114834-A | antidiabetic agent | OTSUKA PHARMA CO LTD (JP) | 1996-01-10 | — | — | CN | disclosed |
| EP-0670831-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-09-13 | — | — | EP | disclosed |
| WO-1995009159-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1995-04-06 | — | — | WO | disclosed |