Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN4A | P35499 | 9/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SCN1A | P35498 | 2/20 | 0.41 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.41 |
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.41 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.41 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.41 |
| ▸ | GBA1 | P04062 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13570163 | 0.84 | TAAR1 (0.59) | SCN4ATAAR1CYP1A2HTR2AHTR2B | |
| SCHEMBL13344106 | 0.81 | GABRA1 (0.43) | SCN4ATSHRLMNASCN1ASCN5A | |
| SCHEMBL4513903 | 0.79 | SCN4A (0.41) | SCN4ATSHRLMNASCN1ASCN5A | |
| SCHEMBL4897798 | 0.79 | PDCD1 (0.41) | SCN4ATSHRLMNASCN1ASCN5A | |
| SCHEMBL11088431 | 0.79 | SCN8A (0.40) | SCN4ATSHRLMNASCN1ASCN5A | |
| SCHEMBL24378512 | 0.79 | SCN8A (0.40) | SCN4ATSHRLMNASCN1ASCN5A | |
| SCHEMBL622628 | 0.79 | CA12 (0.53) | TAAR1TSHRLMNACYP1A2CYP3A4 | |
| SCHEMBL11123175 | 0.79 | SCN8A (0.40) | SCN4ATAAR1TSHRLMNASCN1A | |
| SCHEMBL9112957 | 0.79 | SCN8A (0.40) | SCN4ATSHRLMNASCN1ASCN5A | |
| SCHEMBL11436863 | 0.79 | ALDH1A1 (0.40) | TAAR1TSHRLMNACYP3A4HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12606520-B2 | Calpain-2 inhibitor compounds and methods of treatment | WESTERN UNIVERSITY OF HEALTH SCIENCES (US) | 2026-04-21 | — | — | US | disclosed |
| US-20230091121-A1 | CALPAIN-2 INHIBITOR COMPOUNDS AND METHODS OF TREATMENT | UNITED STATES GOVERNMENT | 2023-03-23 | — | — | US | disclosed |
| WO-2021163631-A1 | CALPAIN-2 INHIBITOR COMPOUNDS AND METHODS OF TREATMENT | WESTERN UNIVERSITY OF HEALTH SCIENCES (US) | 2021-08-19 | — | — | WO | disclosed |
| US-8557853-B2 | Aryl fluoroethyl ureas acting as alpha 2 adrenergic agents | ALLERGAN, INC. (US) | 2013-10-15 | — | — | US | disclosed |
| US-20080194650-A1 | ARYL FLUOROETHYL UREAS ACTING AS ALPHA 2 ADRENERGIC AGENTS | ALLERGHAN, INC. | 2008-08-14 | — | — | US | disclosed |
| US-20040063643-A1 | Bombesin antagonists | PFIZER INC. | 2004-04-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230091121-A1 | CALPAIN-2 INHIBITOR COMPOUNDS AND METHODS OF TREATMENT | CAPN2, CAPNS1, CAPN1 | SCN4A 1780/4885TAAR1 4408/4885TSHR 4808/4885 |
| US-12606520-B2 | Calpain-2 inhibitor compounds and methods of treatment | CAPN2, CAPN1, CAPNS1 | SCN4A 1160/4885TAAR1 4430/4885TSHR 4532/4885 |
| US-20040063643-A1 | Bombesin antagonists | BRS3, NPSR1, GNRHR | SCN4A 2154/4885TAAR1 131/4885TSHR 1578/4885 |
| US-20080194650-A1 | ARYL FLUOROETHYL UREAS ACTING AS ALPHA 2 ADRENERGIC AGENTS | ADRB2, ADRA2C, ADRA2A | SCN4A 701/4885TAAR1 27/4885TSHR 233/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.