Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 12/20 | 0.39 |
| ▸ | DBF4 | Q9UBU7 | 12/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 7/20 | 0.39 |
| ▸ | CDK2 | P24941 | 6/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 5/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2635386 | 0.92 | CDC7 (0.42) | CDC7DBF4ROCK1CDK2CCNE1 | |
| SCHEMBL3008443 | 0.86 | PLA2G10 (0.38) | — | |
| SCHEMBL9034401 | 0.84 | GSK3B (0.41) | CDC7DBF4ROCK1CDK2CCNE1 | |
| SCHEMBL9033357 | 0.82 | GCGR (0.39) | MAPK14 | |
| SCHEMBL9034121 | 0.82 | APP (0.41) | — | |
| SCHEMBL27999718 | 0.81 | PTGS1 (0.33) | — | |
| SCHEMBL423920 | 0.77 | PLA2G10 (0.41) | — | |
| SCHEMBL5466664 | 0.77 | ESR1 (0.36) | — | |
| SCHEMBL21110937 | 0.75 | HTR2C (0.38) | — | |
| SCHEMBL7223952 | 0.75 | ALDH1A1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995007275-A1 | PHOTOCHROMIC COMPOUNDS, METHODS AND INTERMEDIATES FOR PRODUCING THEM AND THEIR USE | CIBA-GEIGY AG (CH) | 1995-03-16 | — | — | WO | disclosed |