Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | TGM2 | P21980 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | F13A1 | P00488 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TGM1 | P22735 | 1/20 | 0.36 |
| ▸ | TGM3 | Q08188 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9113346 | 0.86 | MAOB (0.45) | ALDH1A1GAAMAOBKDM4ETHRB | |
| SCHEMBL23081898 | 0.84 | MAOB (0.44) | ALDH1A1GAAMAOBKDM4ETHRB | |
| SCHEMBL7890748 | 0.80 | CYP1A1 (0.55) | ALDH1A1GAAMAOBTHRBMEN1 | |
| SCHEMBL12803387 | 0.79 | ALDH1A1 (0.53) | ALDH1A1GAAMEN1KMT2APOLB | |
| SCHEMBL7816692 | 0.79 | POLB (0.66) | ALDH1A1GAAMEN1KMT2APOLB | |
| SCHEMBL28444124 | 0.79 | TGM2 (0.59) | ALDH1A1GAAKDM4ETHRBMEN1 | |
| SCHEMBL2576588 | 0.78 | MAOB (0.61) | ALDH1A1GAAMAOBKDM4EMEN1 | |
| SCHEMBL28954825 | 0.77 | TRPV1 (0.46) | ALDH1A1GAAMAOBKDM4ETHRB | |
| SCHEMBL13679387 | 0.76 | HDAC3 (0.55) | ALDH1A1THRBMEN1KMT2ALMNA | |
| SCHEMBL7275026 | 0.75 | ALDH1A1 (0.41) | ALDH1A1GAAMAOBKDM4ETHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0670831-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-09-13 | — | — | EP | disclosed |
| WO-1995009159-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1995-04-06 | — | — | WO | disclosed |