Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SGPL1 | O95470 | 4/20 | 0.45 |
| ▸ | SMPD1 | P17405 | 5/20 | 0.43 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.42 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.42 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.41 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.41 |
| ▸ | LAP3 | P28838 | 1/20 | 0.41 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12766767 | 0.81 | SGPL1 (0.48) | SGPL1SMPD1LPAR3LPAR1LPAR2 | |
| Phosphoric Acid SCHEMBL9116919 | 0.81 | LAP3 (0.44) | SMPD1PTPN1S1PR4S1PR1S1PR3 | |
| SCHEMBL9240085 | 0.78 | S1PR4 (0.54) | SGPL1LPAR3LPAR1LPAR2S1PR4 | |
| SCHEMBL15892988 | 0.78 | SGPL1 (0.50) | SGPL1SMPD1LPAR3LPAR1LPAR2 | |
| SCHEMBL6915675 | 0.77 | SGPL1 (0.44) | SGPL1SMPD1LPAR3LPAR1LPAR2 | |
| SCHEMBL9245727 | 0.77 | SGPL1 (0.44) | SGPL1SMPD1LPAR3LPAR1LPAR2 | |
| SCHEMBL11325815 | 0.74 | SMPD1 (0.47) | SGPL1SMPD1LPAR3LPAR1LPAR2 | |
| Phosphoric Acid SCHEMBL670802 | 0.72 | LAP3 (0.53) | SMPD1S1PR4S1PR1S1PR3S1PR2 | |
| Phosphoric Acid SCHEMBL2806140 | 0.72 | LAP3 (0.53) | SMPD1S1PR4S1PR1S1PR3S1PR2 | |
| Phosphoric Acid SCHEMBL4615576 | 0.71 | LAP3 (0.52) | SMPD1S1PR4S1PR1S1PR3S1PR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995021848-A1 | SPHINGOID BASES AND METHODS FOR THEIR PREPARATION AND USE | THE UNITED STATES OF AMERICA, REPRESENTED BY THE (US) | 1995-08-17 | — | — | WO | disclosed |
| US-5430169-A | Method for preparation of sphingoid bases | THE UNITED STATES OF AMERICA REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1995-07-04 | — | — | US | disclosed |