Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LAP3 | P28838 | 2/20 | 0.52 |
| ▸ | FDPS | P14324 | 6/20 | 0.50 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.47 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.47 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.47 |
| ▸ | SMPD1 | P17405 | 5/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL670802 | 0.98 | LAP3 (0.53) | LAP3FDPSS1PR2S1PR1S1PR3 | |
| Phosphoric Acid SCHEMBL2806140 | 0.98 | LAP3 (0.53) | LAP3FDPSS1PR2S1PR1S1PR3 | |
| SCHEMBL5671085 | 0.88 | SPHK1 (0.50) | LAP3 | |
| SCHEMBL10944400 | 0.88 | SPHK1 (0.50) | LAP3 | |
| SCHEMBL10944404 | 0.88 | SPHK1 (0.50) | LAP3 | |
| SCHEMBL4008504 | 0.88 | SPHK1 (0.50) | LAP3 | |
| Phosphoric Acid SCHEMBL28359318 | 0.87 | FDPS (0.59) | LAP3FDPSS1PR2S1PR1S1PR3 | |
| Hydrochloric Acid SCHEMBL5053423 | 0.86 | SPHK1 (0.48) | LAP3 | |
| Bromide SCHEMBL10787697 | 0.86 | SPHK1 (0.48) | LAP3 | |
| SCHEMBL6771978 | 0.84 | FDPS (0.51) | LAP3FDPSS1PR2S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008081348-A2 | METHOD AND COMPOSITION FOR PERMANENTLY SHAPING HAIR | THE PROCTER & GAMBLE COMPANY (US) | 2008-07-10 | — | — | WO | disclosed |
| US-20080025937-A1 | Method and composition for permanently shaping hair | PROCTER & GAMBLE COMPANY, THE | 2008-01-31 | — | — | US | disclosed |
| EP-1880709-A1 | Method and composition for permanently shaping hair | Wella Aktiengesellschaft (DE) | 2008-01-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080025937-A1 | Method and composition for permanently shaping hair | DNMT3A, DNMT1, NACA | LAP3 3612/4885FDPS 4820/4885S1PR2 659/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.