Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LAP3 | P28838 | 2/20 | 0.53 |
| ▸ | FDPS | P14324 | 6/20 | 0.52 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.49 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.49 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.49 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.49 |
| ▸ | SMPD1 | P17405 | 5/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL670802 | 1.00 | LAP3 (0.53) | LAP3FDPSS1PR2S1PR1S1PR3 | |
| Phosphoric Acid SCHEMBL4615576 | 0.98 | LAP3 (0.52) | LAP3FDPSS1PR2S1PR1S1PR3 | |
| SCHEMBL4008504 | 0.90 | SPHK1 (0.50) | LAP3 | |
| SCHEMBL5671085 | 0.90 | SPHK1 (0.50) | LAP3 | |
| SCHEMBL10944404 | 0.90 | SPHK1 (0.50) | LAP3 | |
| SCHEMBL10944400 | 0.90 | SPHK1 (0.50) | LAP3 | |
| Phosphoric Acid SCHEMBL28359318 | 0.89 | FDPS (0.59) | LAP3FDPSS1PR2S1PR1S1PR3 | |
| Hydrochloric Acid SCHEMBL5053423 | 0.88 | SPHK1 (0.48) | LAP3 | |
| Bromide SCHEMBL10787697 | 0.88 | SPHK1 (0.48) | LAP3 | |
| SCHEMBL6771978 | 0.85 | FDPS (0.51) | LAP3FDPSS1PR2S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010096275-A2 | PERSONAL CLEANSING COMPOSITION INCLUDING A STRUCTURED SURFACTANT SYSTEM AND A SUN PROTECTION FACTOR COMPOSITION | THE DIAL CORPORATION (US) | 2010-08-26 | — | — | WO | disclosed |