Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.69 |
| ▸ | NPC1 | O15118 | 2/20 | 0.69 |
| ▸ | CASP3 | P42574 | 2/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.69 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.69 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.69 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.69 |
| ▸ | GAA | P10253 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | HEXA | P06865 | 1/20 | 0.61 |
| ▸ | HEXB | P07686 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | APEX1 | P27695 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | RPS6KA2 | Q15349 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9081746 | 0.90 | CYP1A2 (0.65) | RAB9ANPC1CASP3SMN1; SMN2SENP8 | |
| SCHEMBL10421957 | 0.82 | RAB9A (1.00) | RAB9ANPC1CASP3SMN1; SMN2SENP8 | |
| SCHEMBL7919296 | 0.80 | RAB9A (0.76) | RAB9ANPC1CASP3SMN1; SMN2SENP8 | |
| SCHEMBL10050510 | 0.79 | RAB9A (0.85) | RAB9ANPC1SMN1; SMN2GAAMEN1 | |
| SCHEMBL18501643 | 0.78 | RAB9A (0.83) | RAB9ANPC1SMN1; SMN2GAAMEN1 | |
| SCHEMBL7077653 | 0.78 | MMP2 (0.60) | RAB9ANPC1GAAMEN1KMT2A | |
| SCHEMBL8618065 | 0.77 | NPC1 (0.76) | RAB9ANPC1CASP3SMN1; SMN2SENP8 | |
| SCHEMBL29168851 | 0.77 | RAB9A (0.68) | RAB9ACASP3GAACYP1A2CYP2D6 | |
| SCHEMBL30758623 | 0.77 | RAB9A (0.68) | RAB9ACASP3GAACYP1A2CYP2D6 | |
| SCHEMBL10508468 | 0.77 | RAB9A (0.76) | RAB9ANPC1CASP3SMN1; SMN2SENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1114834-A | antidiabetic agent | OTSUKA PHARMA CO LTD (JP) | 1996-01-10 | — | — | CN | disclosed |
| EP-0670831-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-09-13 | — | — | EP | disclosed |
| WO-1995009159-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1995-04-06 | — | — | WO | disclosed |