Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.77 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | MB | P02144 | 1/20 | 0.47 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.47 |
| ▸ | CA3 | P07451 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | RARG | P13631 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27744035 | 0.87 | POLB (0.59) | POLBRAB9ANR4A1SMN1; SMN2KDM4C | |
| SCHEMBL11235452 | 0.87 | POLB (1.00) | POLBRAB9ANR4A1SMN1; SMN2PKM | |
| SCHEMBL7765889 | 0.86 | POLB (0.76) | POLBRAB9ANR4A1SMN1; SMN2ALDH1A1 | |
| SCHEMBL24198479 | 0.85 | ALDH1A1 (0.58) | POLBRAB9ASMN1; SMN2KDM4CPKM | |
| SCHEMBL11582150 | 0.83 | POLB (0.54) | POLBSMN1; SMN2KDM4CPKMALDH1A1 | |
| SCHEMBL925741 | 0.82 | SMN1; SMN2 (0.57) | POLBRAB9ASMN1; SMN2KDM4CPKM | |
| SCHEMBL30621955 | 0.82 | SMN1; SMN2 (0.57) | POLBRAB9ASMN1; SMN2KDM4CPKM | |
| SCHEMBL27723422 | 0.81 | POLB (0.52) | POLBRAB9ASMN1; SMN2KDM4CPKM | |
| SCHEMBL170522 | 0.81 | KDM4C (0.62) | POLBSMN1; SMN2KDM4CPKMALDH1A1 | |
| SCHEMBL30076649 | 0.81 | KDM4C (0.62) | POLBSMN1; SMN2KDM4CPKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022008678-A2 | AURONE DERIVATIVES AND USES THEREOF FOR CONTROLLING BACTERIA AND/OR FUNGI | UNIVERSITE D'AIX-MARSEILLE (FR) | 2022-01-13 | — | — | WO | disclosed |
| WO-1995014469-A1 | NOVEL SPIROCYCLES | MERCK & CO., INC. (US) | 1995-06-01 | — | — | WO | disclosed |
| US-5403846-A | Antiarrhythmic agents | MERCK & CO., INC. (US) | 1995-04-04 | — | — | US | disclosed |