SCHEMBL7765889

SCHEMBL7765889

CCC(=O)c1ccc(NC(C)=O)cc1C(=O)CC

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.76
RAB9A P51151 3/20 0.57
NR4A1 P22736 1/20 0.57
TDP1 Q9NUW8 4/20 0.51
SMN1; SMN2 Q16637 2/20 0.50
HTT P42858 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
NPC1 O15118 2/20 0.47
RORC P51449 1/20 0.46
CDK1 P06493 1/20 0.46
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
MAPT P10636 2/20 0.46
ALDH1A1 P00352 2/20 0.46
KDM4E B2RXH2 1/20 0.46
GLA P06280 1/20 0.46
TNNI3 P19429 1/20 0.46
TNNT2 P45379 1/20 0.46
TNNC1 P63316 1/20 0.46
RUNX1 Q01196 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11235452 0.86 POLB (1.00) POLBRAB9ANR4A1TDP1SMN1; SMN2
SCHEMBL9114491 0.86 POLB (0.77) POLBRAB9ANR4A1TDP1SMN1; SMN2
SCHEMBL9821067 0.85 POLB (0.69) POLBRAB9ANR4A1TDP1SMN1; SMN2
SCHEMBL10965331 0.85 POLB (0.69) POLBRAB9ANR4A1TDP1SMN1; SMN2
SCHEMBL3619479 0.76 ALDH1A1 (0.70) POLBRAB9ANR4A1TDP1SMN1; SMN2
SCHEMBL2500845 0.76 MYC (0.61) POLBRAB9ATDP1SMN1; SMN2HTT
SCHEMBL21765699 0.75 RAB9A (0.72) POLBRAB9ANR4A1SMN1; SMN2L3MBTL1
SCHEMBL14584390 0.75 RAB9A (0.72) POLBRAB9ANR4A1TDP1SMN1; SMN2
SCHEMBL8888227 0.74 POLB (0.55) POLBRAB9ANR4A1TDP1SMN1; SMN2
SCHEMBL6686241 0.74 RAB9A (0.70) POLBRAB9ANR4A1SMN1; SMN2L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0617005-B1 Triarylamine compound, process for producing the same and electrophotographic photoreceptor using the same FUJI XEROX CO LTD (JP) 2001-06-13 EP disclosed
US-5587263-A STABLE CHARGE TRANSPORT LAYER FUJI XEROX CO., LTD. (JP) 1996-12-24 US disclosed
US-5495049-A CHARGE TRANSFER COMPOUNDS FUJI XEROX CO., LTD. (JP) 1996-02-27 US disclosed
EP-0617005-A2 Triarylamine compound, process for producing the same and electrophotographic photoreceptor using the same FUJI XEROX CO., LTD. (JP) 1994-09-28 EP disclosed