Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8950361 | 0.73 | LMNA (0.38) | LMNAHPGDTSHRKMT2AMAPT | |
| SCHEMBL9057290 | 0.68 | NPC1 (0.32) | NPC1RAB9A | |
| SCHEMBL15004854 | 0.59 | MAPK1 (0.58) | LMNAHPGDTSHRKMT2AMAPT | |
| SCHEMBL10516113 | 0.59 | NPC1 (0.73) | LMNAHPGDTSHRKMT2AMAPT | |
| Methyl 4-Methoxybenzoate SCHEMBL231243 | 0.59 | CA1 (1.00) | LMNATSHRKMT2AMAPTKDM4E | |
| SCHEMBL2273711 | 0.58 | CA1 (0.88) | LMNAHPGDKMT2AMAPTALDH1A1 | |
| SCHEMBL6132300 | 0.58 | CA1 (0.64) | LMNATSHRKMT2AMAPTALDH1A1 | |
| SCHEMBL6727704 | 0.57 | MEN1 (0.47) | HPGDKMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL922692 | 0.57 | KMT2A (0.69) | LMNAHPGDKMT2AMAPTALDH1A1 | |
| SCHEMBL25308227 | 0.57 | TUBB4A (0.60) | KMT2AMAPTALDH1A1KDM4ECA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995019981-A1 | THIENOTHIAZINE SULFONAMIDE DERIVATIVES PROCESS AND INTERMEDIATES FOR THEIR PREPARATION AND THEIR USE AS CARBONIC ANHYDRASE INHIBITORS | ALCON LABORATORIES, INC. (US) | 1995-07-27 | — | — | WO | disclosed |