Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8950606 | 0.80 | CA2 (0.36) | LMNAMAPTMAPK10ALDH1A1CA2 | |
| SCHEMBL9115098 | 0.73 | LMNA (0.41) | LMNAMAPTKDM4EHPGDMAPK10 | |
| SCHEMBL8950076 | 0.71 | FEN1 (0.46) | LMNAMAPTKDM4EHPGDMAPK10 | |
| SCHEMBL8950208 | 0.71 | CA2 (0.33) | CA2 | |
| SCHEMBL8950271 | 0.71 | CYP4A11 (0.34) | LMNAKMT2AL3MBTL1POLB | |
| SCHEMBL20487232 | 0.58 | MEN1 (0.74) | MAPTKMT2AMEN1TDP1TP53 | |
| SCHEMBL10516113 | 0.57 | NPC1 (0.73) | LMNAMAPTKDM4EHPGDNPSR1 | |
| SCHEMBL15004854 | 0.57 | MAPK1 (0.58) | LMNAMAPTKDM4EHPGDALDH1A1 | |
| Methyl 4-Methoxybenzoate SCHEMBL231243 | 0.57 | CA1 (1.00) | LMNAMAPTKDM4ECA1CA2 | |
| SCHEMBL11502770 | 0.57 | HSD11B1 (0.43) | LMNAKDM4EALDH1A1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5538966-A | ENZYME INHIBITORS FOR TREATMENT OF GLAUCOMA | ALCON LABORATORIES, INC. (US) | 1996-07-23 | — | — | US | disclosed |