SCHEMBL9115577

SCHEMBL9115577

CC(C)=CC(C)(C)COC(=O)CC(C)C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP1 P03956 1/20 0.38
MMP2 P08253 1/20 0.38
MMP3 P08254 1/20 0.38
MMP9 P14780 1/20 0.38
MMP13 P45452 1/20 0.38
ALDH1A1 P00352 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
PRKCA P17252 3/20 0.35
PRKD3 O94806 1/20 0.32
PRKCG P05129 1/20 0.32
PRKCB P05771 1/20 0.32
PRKCH P24723 1/20 0.32
PRKCI P41743 1/20 0.32
PRKCE Q02156 1/20 0.32
PRKCQ Q04759 1/20 0.32
PRKCZ Q05513 1/20 0.32
PRKCD Q05655 1/20 0.32
PRKD1 Q15139 1/20 0.32
GLA P06280 1/20 0.31
MIF P14174 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3095915 0.81 MMP1 (0.40) MMP1MMP2MMP3MMP9MMP13
SCHEMBL9116098 0.79 ALDH1A1 (0.34) ALDH1A1
SCHEMBL3442983 0.77 MMP1 (0.41) MMP1MMP2MMP3MMP9MMP13
SCHEMBL8215989 0.77 MMP1 (0.41) MMP1MMP2MMP3MMP9MMP13
SCHEMBL9116010 0.77 ALDH1A1 (0.39) ALDH1A1TDP1
SCHEMBL8216917 0.74 MMP1 (0.42) MMP1MMP2MMP3MMP9MMP13
SCHEMBL28828335 0.73 CYP2C19 (0.39) MMP1MMP2MMP3MMP9MMP13
SCHEMBL12192460 0.73 MMP1 (0.38) MMP1MMP2MMP3MMP9MMP13
SCHEMBL18908741 0.72 MMP1 (0.37) MMP1MMP2MMP3MMP9MMP13
SCHEMBL2690771 0.71 HTT (0.50) MMP1MMP2MMP3MMP9MMP13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1995021606-A1 2,2,4-TRIMETHYL-PENTEN-1-YL COMPOUNDS, FRAGRANCE AND FLAVOR COMPOSITIONS UNION CAMP CORPORATION (US) 1995-08-17 WO disclosed