Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 2/20 | 0.51 |
| ▸ | PTPRA | P18433 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8844316 | 0.87 | FDPS (0.54) | FDPSPTPRASMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL9114269 | 0.79 | ERAP1 (0.57) | SMN1; SMN2 | |
| SCHEMBL8843877 | 0.78 | FDPS (0.60) | FDPSPTPRASMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL7075416 | 0.78 | PTPRA (0.59) | FDPSPTPRASMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL7205140 | 0.77 | PTPRA (0.57) | FDPSPTPRASMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL9114970 | 0.75 | ERAP1 (0.48) | FDPSSMN1; SMN2ALDH1A1RAB9ALMNA | |
| SCHEMBL1768948 | 0.74 | SLC1A5 (0.56) | PTPRASMN1; SMN2CYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL1176394 | 0.74 | SLC1A5 (0.56) | PTPRASMN1; SMN2CYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL30428132 | 0.74 | SLC1A5 (0.56) | PTPRASMN1; SMN2CYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL1130371 | 0.74 | PTPRA (0.54) | FDPSPTPRASMN1; SMN2CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995011249-A1 | 2,4-DIPHOSPHONOGLUTARIC ACID DERIVATIVES, METHODS OF PREPARING THEM AND DRUGS CONTAINING THEM | BOEHRINGER MANNHEIM GMBH (DE) | 1995-04-27 | — | — | WO | disclosed |