Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | PGR | P06401 | 3/20 | 0.56 |
| ▸ | AR | P10275 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.56 |
| ▸ | SHBG | P04278 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.56 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | ESR1 | P03372 | 1/20 | 0.56 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6301574 | 0.87 | CYP19A1 (0.56) | CYP19A1CYP3A4LMNAPGRAR | |
| SCHEMBL4013306 | 0.87 | CYP19A1 (0.56) | CYP19A1CYP3A4LMNAPGRAR | |
| SCHEMBL6231408 | 0.85 | NR1I2 (0.42) | CYP19A1CYP3A4LMNAPGRAR | |
| SCHEMBL11134362 | 0.84 | CYP19A1 (0.54) | CYP19A1CYP3A4LMNAPGRAR | |
| SCHEMBL10449146 | 0.83 | CYP19A1 (0.52) | CYP19A1CYP3A4LMNAPGRAR | |
| SCHEMBL6244897 | 0.83 | SERPINA6 (0.54) | CYP19A1CYP3A4LMNAPGRAR | |
| SCHEMBL13216466 | 0.82 | CYP19A1 (0.66) | CYP19A1CYP3A4LMNAPGRAR | |
| SCHEMBL11977689 | 0.82 | CYP19A1 (0.66) | CYP19A1CYP3A4LMNAPGRAR | |
| SCHEMBL922877 | 0.82 | CYP19A1 (0.66) | CYP19A1CYP3A4LMNAPGRAR | |
| SCHEMBL19608861 | 0.82 | CYP19A1 (0.66) | CYP19A1CYP3A4LMNAPGRAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0664811-A1 | GESTAGENICALLY ACTIVE 19,11-BRIDGED 4-ESTRENES. | SCHERING AG (DE) | 1995-08-02 | — | — | EP | disclosed |
| WO-1994009025-A1 | GESTAGENICALLY ACTIVE 19,11-BRIDGED 4-ESTRENES | SCHERING AKTIENGESELLSCHAFT (DE) | 1994-04-28 | — | — | WO | disclosed |