Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.66 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | SHBG | P04278 | 2/20 | 0.62 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.62 |
| ▸ | THRB | P10828 | 1/20 | 0.62 |
| ▸ | PGR | P06401 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | ESR1 | P03372 | 1/20 | 0.56 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.56 |
| ▸ | AR | P10275 | 3/20 | 0.55 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL922877 | 1.00 | CYP19A1 (0.66) | CYP19A1SERPINA6ALDH1A1SHBGSLC22A1 | |
| SCHEMBL19608861 | 1.00 | CYP19A1 (0.66) | CYP19A1SERPINA6ALDH1A1SHBGSLC22A1 | |
| SCHEMBL26425075 | 1.00 | CYP19A1 (0.66) | CYP19A1SERPINA6ALDH1A1SHBGSLC22A1 | |
| SCHEMBL11977689 | 1.00 | CYP19A1 (0.66) | CYP19A1SERPINA6ALDH1A1SHBGSLC22A1 | |
| Cyclohexane Propionic Acid SCHEMBL27589911 | 0.84 | SERPINA6 (0.49) | CYP19A1SERPINA6ALDH1A1SHBGSLC22A1 | |
| SCHEMBL9116613 | 0.82 | CYP19A1 (0.60) | CYP19A1SERPINA6ALDH1A1SHBGSLC22A1 | |
| SCHEMBL11795958 | 0.81 | AR (0.64) | CYP19A1SERPINA6ALDH1A1SHBGSLC22A1 | |
| SCHEMBL9948814 | 0.81 | CYP19A1 (0.44) | CYP19A1SERPINA6ALDH1A1SHBGSLC22A1 | |
| SCHEMBL9948623 | 0.81 | CYP19A1 (0.44) | CYP19A1SERPINA6ALDH1A1SHBGSLC22A1 | |
| SCHEMBL24102654 | 0.80 | PGR (0.56) | CYP19A1SERPINA6ALDH1A1SHBGSLC22A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4164743-A2 | MONOMERIC AND OLIGOMERIC COMPOUND EMBODIMENTS AS CONTRACEPTIVES AND THERAPIES AND METHODS OF MAKING AND USING THE SAME | The United States of America, as represented by The Secretary, Department of Health and Human Services (US) | 2023-04-19 | — | — | EP | disclosed |
| US-7772218-B2 | Synthesis of anti-estrogenic and other therapeutic steroids from 21-hydroxy-19-norpregna-4-en-3-one | SRI INTERNATIONAL (US) | 2010-08-10 | — | — | US | disclosed |