Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.66 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | SHBG | P04278 | 2/20 | 0.62 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.62 |
| ▸ | THRB | P10828 | 1/20 | 0.62 |
| ▸ | PGR | P06401 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | ESR1 | P03372 | 1/20 | 0.56 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.56 |
| ▸ | AR | P10275 | 3/20 | 0.55 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19608861 | 1.00 | CYP19A1 (0.66) | CYP19A1SERPINA6ALDH1A1SHBGSLC22A1 | |
| SCHEMBL26425075 | 1.00 | CYP19A1 (0.66) | CYP19A1SERPINA6ALDH1A1SHBGSLC22A1 | |
| SCHEMBL11977689 | 1.00 | CYP19A1 (0.66) | CYP19A1SERPINA6ALDH1A1SHBGSLC22A1 | |
| SCHEMBL13216466 | 1.00 | CYP19A1 (0.66) | CYP19A1SERPINA6ALDH1A1SHBGSLC22A1 | |
| Cyclohexane Propionic Acid SCHEMBL27589911 | 0.84 | SERPINA6 (0.49) | CYP19A1SERPINA6ALDH1A1SHBGSLC22A1 | |
| SCHEMBL9116613 | 0.82 | CYP19A1 (0.60) | CYP19A1SERPINA6ALDH1A1SHBGSLC22A1 | |
| SCHEMBL11795958 | 0.81 | AR (0.64) | CYP19A1SERPINA6ALDH1A1SHBGSLC22A1 | |
| SCHEMBL9948814 | 0.81 | CYP19A1 (0.44) | CYP19A1SERPINA6ALDH1A1SHBGSLC22A1 | |
| SCHEMBL9948623 | 0.81 | CYP19A1 (0.44) | CYP19A1SERPINA6ALDH1A1SHBGSLC22A1 | |
| SCHEMBL24102654 | 0.80 | PGR (0.56) | CYP19A1SERPINA6ALDH1A1SHBGSLC22A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 117 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1649283-B1 | METHOD FOR MEASURING AROMATASE ACTIVITY | GE HEALTHCARE UK LTD (GB) | 2014-06-18 | — | — | EP | claimed |
| US-8334387-B2 | Method for measuring aromatase activity | GE HEALTHCARE UK LIMITED (GB) | 2012-12-18 | — | — | US | claimed |
| US-20110014641-A1 | METHOD FOR MEASURING AROMATASE ACTIVITY | GE HEALTHCARE UK LIMITED (GB) | 2011-01-20 | — | — | US | claimed |
| US-7829714-B2 | Method for measuring aromatase activity | GE HEALTHCARE LIMITED (GB) | 2010-11-09 | — | — | US | claimed |
| US-20090156843-A1 | PROCESS FOR AROMATIZING 19-NORANDROST-4-EN-3-ONES TO ESTRA-1,3,5(10)-TRIENES | BAYER SCHERING PHARMA AG (DE) | 2009-06-18 | — | — | US | claimed |
| EP-1239829-B1 | DEVICES FOR THE DELIVERY OF DRUGS HAVING ANTIPROGESTINIC PROPERTIES | BAYER SCHERING PHARMA OY (FI) | 2008-07-23 | — | — | EP | claimed |
| US-20070184429-A1 | Method for measuring aromatase activity | GE HEALTHCARE UK LIMITED (GB) | 2007-08-09 | — | — | US | claimed |
| EP-1649283-A2 | METHOD FOR MEASURING AROMATASE ACTIVITY | GE Healthcare UK Limited (GB) | 2006-04-26 | — | — | EP | claimed |
| WO-2005012901-A2 | METHOD FOR MEASURING AROMATASE ACTIVITY | AMERSHAM BIOSCIENCES UK LIMITED (GB) | 2005-02-10 | — | — | WO | claimed |
| EP-0114984-B1 | PROCESS FOR THE PREPARATION OF 3,11-ALPHA DIHYDROXY-1,3,5(10) ESTRATRIENE DERIVATIVES | SCHERING AKTIENGESELLSCHAFT (DE) | 1987-10-21 | — | — | EP | claimed |
| EP-0137434-A2 | Estrane and androstane derivatives, process for their preparation and pharmaceutical preparations containing them | SCHERING AKTIENGESELLSCHAFT (DE) | 1985-04-17 | — | — | EP | claimed |
| CN-116334113-A | Conditionally active heterodimeric polypeptides and methods of use thereof | 加利福尼亚大学董事会 | 2023-06-27 | — | — | CN | disclosed |
| US-10940205-B2 | Compositions of pharmaceutical actives containing diethylene glycol monoethyl ether or other alkyl derivatives | THEMIS MEDICARE LIMITED (IN) | 2021-03-09 | — | — | US | disclosed |
| CN-111840246-A | Formulations and methods for vaginal delivery of antiprogestins | 艾尔建制药国际有限公司 | 2020-10-30 | — | — | CN | disclosed |
| US-20180071390-A1 | COMPOSITIONS OF PHARMACEUTICAL ACTIVES CONTAINING DIETHYLENE GLYCOL MONOETHYL ETHER OR OTHER ALKYL DERIVATIVES | THEMIS MEDICARE LIMITED (IN) | 2018-03-15 | — | — | US | disclosed |
| EP-0114984-A2 | Process for the preparation of 3,11-alpha dihydroxy-1,3,5(10) estratriene derivatives | SCHERING AKTIENGESELLSCHAFT (DE) | 1984-08-08 | — | — | EP | disclosed |
| US-4464365-A | 11β-Chloro-Δ15 -steroids, a process for their preparation and pharmaceutical preparations containing them | SCHERING AKTIENGESELLSCHAFT (DE) | 1984-08-07 | — | — | US | disclosed |
| US-4379842-A | Process for the manufacture of 1α-hydroxydehydroepiandrosterone | HOFFMANN-LA ROCHE INC. (US) | 1983-04-12 | — | — | US | disclosed |
| US-4000273-A | METHOD FOR THE CONTROL OF FERTILITY | RICHARDSON-MERRELL INC. (US) | 1976-12-28 | — | — | US | disclosed |
| US-3989724-A | Tetrahydropyran-2-ols | HOFFMANN-LA ROCHE INC. (US) | 1976-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180071390-A1 | COMPOSITIONS OF PHARMACEUTICAL ACTIVES CONTAINING DIETHYLENE GLYCOL MONOETHYL ETHER OR OTHER ALKYL DERIVATIVES | DSG1, DEGS1, PLA2G2E | CYP19A1 1344/4885SERPINA6 1891/4885ALDH1A1 2851/4885 |
| US-20090156843-A1 | PROCESS FOR AROMATIZING 19-NORANDROST-4-EN-3-ONES TO ESTRA-1,3,5(10)-TRIENES | CYP19A1, HSD17B11, NR5A1 | CYP19A1 1/4885SERPINA6 991/4885ALDH1A1 83/4885 |
| US-10940205-B2 | Compositions of pharmaceutical actives containing diethylene glycol monoethyl ether or other alkyl derivatives | DSG1, DEGS1, PLA2G2E | CYP19A1 1344/4885SERPINA6 1891/4885ALDH1A1 2851/4885 |
| US-20110014641-A1 | METHOD FOR MEASURING AROMATASE ACTIVITY | CYP19A1, CYP17A1, CYP21A2 | CYP19A1 1/4885SERPINA6 483/4885ALDH1A1 223/4885 |
| US-20070184429-A1 | Method for measuring aromatase activity | CYP19A1, CYP17A1, CYP21A2 | CYP19A1 1/4885SERPINA6 483/4885ALDH1A1 223/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.