SCHEMBL9116923

SCHEMBL9116923

Cc1ccc(S(=O)(=O)N[C@H]2CCCC[C@@H]2NC(=O)OC(C)(C)C)cc1

nearest known ligand 0.53

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.50
TSHR P16473 3/20 0.50
CYP3A4 P08684 1/20 0.50
ADORA3 P0DMS8 1/20 0.47
MCOLN2 Q8IZK6 1/20 0.45
MCOLN3 Q8TDD5 1/20 0.45
MCOLN1 Q9GZU1 1/20 0.45
MAOA P21397 1/20 0.44
MAOB P27338 1/20 0.44
HTT P42858 2/20 0.44
HSD17B10 Q99714 1/20 0.44
GAA P10253 1/20 0.43
KCNH2 Q12809 1/20 0.43
NPSR1 Q6W5P4 2/20 0.43
POLB P06746 1/20 0.43
USP2 O75604 1/20 0.43
LMNA P02545 1/20 0.43
MMP13 P45452 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4367542 1.00 ALDH1A1 (0.50) ALDH1A1TSHRCYP3A4ADORA3MCOLN2
SCHEMBL4401404 0.98 TSHR (0.48) ALDH1A1TSHRCYP3A4ADORA3MCOLN2
SCHEMBL30065513 0.86 ALOX5 (0.46) ALDH1A1MAOAMAOBHTTNPSR1
SCHEMBL11807856 0.82 ALDH1A1 (0.57) ALDH1A1TSHRCYP3A4ADORA3HTT
SCHEMBL3970619 0.81 ALDH1A1 (0.72) ALDH1A1TSHRCYP3A4ADORA3MCOLN2
SCHEMBL4624018 0.80 TSHR (0.59) ALDH1A1TSHRCYP3A4ADORA3HTT
SCHEMBL14368963 0.79 MAOA (0.43) ALDH1A1TSHRADORA3MAOAMAOB
SCHEMBL25318976 0.78 MAOA (0.42) ALDH1A1TSHRADORA3MAOAMAOB
SCHEMBL6639675 0.77 MAOA (0.43) TSHRADORA3MAOAMAOBPOLB
SCHEMBL16057394 0.77 TSHR (0.61) ALDH1A1TSHRCYP3A4ADORA3MCOLN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1995028968-A1 DIAGNOSTIC IMAGE ANALYSIS WITH METAL COMPLEXES MONSANTO COMPANY (US) 1995-11-02 WO disclosed