Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7572620 | 0.79 | NPC1 (0.56) | SMN1; SMN2NPC1CASP3SENP8SENP7 | |
| SCHEMBL7572363 | 0.76 | NPC1 (0.56) | SMN1; SMN2NPC1CHRM5 | |
| SCHEMBL7573586 | 0.76 | NPSR1 (0.45) | — | |
| SCHEMBL7575022 | 0.76 | CHRM5 (0.56) | SMN1; SMN2NPC1CHRM5 | |
| SCHEMBL7579153 | 0.75 | CHRM5 (0.60) | SMN1; SMN2NPC1CHRM5 | |
| SCHEMBL13107935 | 0.74 | LMNA (0.46) | CA12CA2CA9SMN1; SMN2NPC1 | |
| SCHEMBL3444467 | 0.74 | LMNA (0.46) | CA12CA2CA9SMN1; SMN2NPC1 | |
| SCHEMBL3444466 | 0.74 | LMNA (0.46) | CA12CA2CA9SMN1; SMN2NPC1 | |
| SCHEMBL20115842 | 0.70 | ALDH1A1 (0.35) | CA12CA2CA9 | |
| SCHEMBL7573957 | 0.70 | MEN1 (0.57) | CA2SMN1; SMN2NPC1CASP3SENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995021848-A1 | SPHINGOID BASES AND METHODS FOR THEIR PREPARATION AND USE | THE UNITED STATES OF AMERICA, REPRESENTED BY THE (US) | 1995-08-17 | — | — | WO | disclosed |
| US-5430169-A | Method for preparation of sphingoid bases | THE UNITED STATES OF AMERICA REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1995-07-04 | — | — | US | disclosed |