Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9116819 | 0.87 | ALDH1A1 (0.45) | ALDH1A1KDM4EHSD17B10MAPTSMN1; SMN2 | |
| SCHEMBL9239722 | 0.87 | ALDH1A1 (0.38) | TAS1R3TAS1R1ALDH1A1KDM4EHSD17B10 | |
| Hydrochloric Acid SCHEMBL9239730 | 0.86 | ALDH1A1 (0.44) | ALDH1A1KDM4EHSD17B10GAAMAPT | |
| SCHEMBL9241991 | 0.79 | MEN1 (0.35) | TAS1R3TAS1R1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL7470966 | 0.77 | BACE1 (0.38) | NR4A2ABL1ALDH1A1KDM4EPTGS2 | |
| SCHEMBL9115645 | 0.72 | GAA (0.43) | NR4A2ABL1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL4072002 | 0.72 | ALDH1A1 (0.50) | NR4A2ABL1TAS1R3TAS1R1ALDH1A1 | |
| SCHEMBL31069548 | 0.69 | MEP1B (0.48) | NR4A2ABL1TAS1R3TAS1R1ALDH1A1 | |
| SCHEMBL6852879 | 0.68 | CA1 (0.52) | ABL1ALDH1A1KDM4EHSD17B10GAA | |
| SCHEMBL18529866 | 0.68 | ABL1 (0.49) | ABL1ALDH1A1KDM4EHSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995025105-A1 | ISOXAZOLE DERIVATIVES AND THEIR USE AS HERBICIDES | RHONE-POULENC AGRICULTURE LTD (GB) | 1995-09-21 | — | — | WO | disclosed |