Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9116820 | 0.93 | MAOB (0.51) | MAOBKCNH2ALDH1A1KDM4ERAB9A | |
| SCHEMBL9116078 | 0.89 | HTR2A (0.51) | ALDH1A1KDM4ESMN1; SMN2CYP3A4HRH3 | |
| SCHEMBL9117021 | 0.89 | KCNH2 (0.48) | KCNH2KDM4ECYP3A4HTR2A | |
| SCHEMBL9115389 | 0.86 | MAPT (0.45) | KCNH2ALDH1A1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL9114665 | 0.84 | DRD2 (0.49) | ALDH1A1KDM4ESMN1; SMN2CYP3A4HTR2A | |
| SCHEMBL9117345 | 0.84 | CHRM2 (0.49) | MAOBKCNH2ALDH1A1KDM4EHRH3 | |
| SCHEMBL9115835 | 0.81 | HTR2A (0.50) | ALDH1A1KDM4ESMN1; SMN2CYP3A4HTR2A | |
| SCHEMBL9115981 | 0.81 | HTR2A (0.50) | ALDH1A1KDM4ESMN1; SMN2CYP3A4HTR2A | |
| SCHEMBL9115963 | 0.81 | HTR2A (0.50) | ALDH1A1KDM4ESMN1; SMN2CYP3A4HTR2A | |
| SCHEMBL9117274 | 0.81 | ALDH1A1 (0.54) | KCNH2ALDH1A1KDM4EMEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995025731-A1 | NOVEL 3-(φ-(4-BENZOYLPIPERIDINO)ALKYL)-4H-BENZOPYRAN-4-ONES, PREPARATION AND THERAPEUTICAL USE THEREOF | PIERRE FABRE MEDICAMENT (FR) | 1995-09-28 | — | — | WO | claimed |
| WO-1995025731-A1 | NOVEL 3-(φ-(4-BENZOYLPIPERIDINO)ALKYL)-4H-BENZOPYRAN-4-ONES, PREPARATION AND THERAPEUTICAL USE THEREOF | PIERRE FABRE MEDICAMENT (FR) | 1995-09-28 | — | — | WO | disclosed |