Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.49 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.49 |
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | CPS1 | P31327 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9116840 | 0.89 | KCNH2 (0.45) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL9116078 | 0.87 | HTR2A (0.51) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL9117040 | 0.84 | MAOB (0.51) | KCNH2MAOBHRH3KDM4EALDH1A1 | |
| SCHEMBL9114665 | 0.83 | DRD2 (0.49) | KDM4EALDH1A1 | |
| SCHEMBL9116097 | 0.83 | ALDH1A1 (0.51) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL9115981 | 0.80 | HTR2A (0.50) | KDM4EALDH1A1 | |
| SCHEMBL9115963 | 0.80 | HTR2A (0.50) | KDM4EALDH1A1 | |
| SCHEMBL9115835 | 0.80 | HTR2A (0.50) | KDM4EALDH1A1 | |
| SCHEMBL9115680 | 0.78 | HTR2A (0.49) | KDM4E | |
| SCHEMBL9117585 | 0.77 | HTR2A (0.51) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995025731-A1 | NOVEL 3-(φ-(4-BENZOYLPIPERIDINO)ALKYL)-4H-BENZOPYRAN-4-ONES, PREPARATION AND THERAPEUTICAL USE THEREOF | PIERRE FABRE MEDICAMENT (FR) | 1995-09-28 | — | — | WO | claimed |
| WO-1995025731-A1 | NOVEL 3-(φ-(4-BENZOYLPIPERIDINO)ALKYL)-4H-BENZOPYRAN-4-ONES, PREPARATION AND THERAPEUTICAL USE THEREOF | PIERRE FABRE MEDICAMENT (FR) | 1995-09-28 | — | — | WO | disclosed |