SCHEMBL9117350

SCHEMBL9117350

CCC(CC)Cc1ccc(OCc2ccc(Cl)cc2)c(Cl)c1

nearest known ligand 0.49

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MRGPRX4 Q96LA9 7/20 0.49
CCR5 P51681 6/20 0.46
TACR2 P21452 1/20 0.46
HPGD P15428 2/20 0.45
NPC1 O15118 1/20 0.45
RAB9A P51151 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
CSNK2A1 P68400 2/20 0.43
USP2 O75604 1/20 0.43
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
ATM Q13315 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9291860 0.90 RAB9A (0.44) MRGPRX4HPGDNPC1RAB9ASMN1; SMN2
SCHEMBL9618514 0.83 NPC1 (0.51) HPGDNPC1RAB9ASMN1; SMN2CSNK2A1
SCHEMBL13321693 0.79 MRGPRX4 (0.71) MRGPRX4CCR5HPGDNPC1RAB9A
SCHEMBL9119032 0.76 MRGPRX4 (0.49) MRGPRX4CCR5TACR2HPGDNPC1
SCHEMBL9119360 0.75 MRGPRX4 (0.48) MRGPRX4CCR5TACR2HPGDNPC1
SCHEMBL24827443 0.75 SLC6A2 (0.56) SMN1; SMN2
SCHEMBL14854821 0.73 MRGPRX4 (0.55) MRGPRX4CCR5HPGDNPC1RAB9A
SCHEMBL8414105 0.73 SMN1; SMN2 (0.53) MRGPRX4HPGDNPC1RAB9ASMN1; SMN2
SCHEMBL9120596 0.71 RAB9A (0.48) MRGPRX4CCR5TACR2HPGDNPC1
SCHEMBL11512939 0.71 MRGPRX4 (0.69) MRGPRX4HPGDNPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0504812-B1 Aromatic compounds, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL CO (JP) 1995-09-06 EP claimed
US-5302619-A Aromatic compounds, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-04-12 US claimed
US-5262441-A APPLYING INSECTICIDE TO INSECT OR LOCUS WHERE INSECT PROPAGATES SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1993-11-16 US claimed
EP-0504812-A2 Aromatic compounds, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-09-23 EP claimed
EP-0504812-B1 Aromatic compounds, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL CO (JP) 1995-09-06 EP disclosed
US-5302619-A Aromatic compounds, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-04-12 US disclosed
US-5262441-A APPLYING INSECTICIDE TO INSECT OR LOCUS WHERE INSECT PROPAGATES SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1993-11-16 US disclosed
EP-0504812-A2 Aromatic compounds, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-09-23 EP disclosed