Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 10/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | BID | P55957 | 1/20 | 0.45 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.45 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.45 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.45 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11786282 | 0.86 | KDM4E (0.56) | SIGMAR1L3MBTL1MEN1KMT2AKDM4E | |
| SCHEMBL23280438 | 0.81 | LIPG (0.52) | CYP3A4BIDBCL2L1MCL1BAK1 | |
| SCHEMBL9116254 | 0.80 | L3MBTL1 (0.60) | SIGMAR1L3MBTL1CYP3A4MCL1 | |
| SCHEMBL15662944 | 0.79 | KCNH2 (0.62) | SIGMAR1KDM4ECYP3A4SLC6A2SLC6A4 | |
| SCHEMBL7184664 | 0.79 | KCNH2 (0.62) | SIGMAR1KDM4ECYP3A4SLC6A2SLC6A4 | |
| SCHEMBL8857520 | 0.79 | CYP3A4 (0.45) | KDM4ECYP3A4MAPTTAAR1SLC6A2 | |
| SCHEMBL27378152 | 0.79 | KCNH2 (0.62) | SIGMAR1KDM4ECYP3A4SLC6A2SLC6A4 | |
| SCHEMBL3130671 | 0.78 | SLC6A2 (0.67) | SIGMAR1L3MBTL1MEN1KMT2AKDM4E | |
| SCHEMBL28963713 | 0.77 | HTR2A (0.58) | SIGMAR1L3MBTL1BIDBCL2L1MCL1 | |
| SCHEMBL29588181 | 0.77 | HTR2A (0.58) | SIGMAR1L3MBTL1BIDBCL2L1MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995017888-A1 | PHENYLMETHYL HEXANAMIDES, AND THE USE THEREOF | SMITHKLINE BEECHAM CORPORATION (US) | 1995-07-06 | — | — | WO | disclosed |