SCHEMBL9117929

SCHEMBL9117929

Cc1cn(C)c(=O)n(CCO)c1=O

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.42
KDM4E B2RXH2 2/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
ALDH1A1 P00352 3/20 0.41
LMNA P02545 2/20 0.41
PDE4A P27815 1/20 0.39
PDE4B Q07343 1/20 0.39
PDE4C Q08493 1/20 0.39
PDE4D Q08499 1/20 0.39
TRPC5 Q9UL62 1/20 0.35
ADORA3 P0DMS8 1/20 0.34
POLB P06746 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP2C9 P11712 1/20 0.34
TSHR P16473 2/20 0.33
THRB P10828 1/20 0.33
MAPK1 P28482 1/20 0.33
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7606566 0.86 TRPC5 (0.43) KDM4EMEN1KMT2APDE4APDE4B
SCHEMBL8071799 0.86 TRPC5 (0.43) KDM4EMEN1KMT2APDE4APDE4B
SCHEMBL6217047 0.82 ADORA2B (0.38) HSD17B10KDM4EALDH1A1LMNAPDE4A
SCHEMBL26940381 0.80 KDM4E (0.42) HSD17B10KDM4EALDH1A1LMNAPDE4A
SCHEMBL15230054 0.79 PDE4A (0.38) HSD17B10KDM4EMEN1KMT2AALDH1A1
SCHEMBL7834052 0.79 PDE4A (0.40) PDE4APDE4BPDE4CPDE4DTRPC5
SCHEMBL19732273 0.77 PDE4A (0.43) HSD17B10KDM4EKMT2AALDH1A1LMNA
SCHEMBL27338495 0.77 ADORA2B (0.47) KDM4EALDH1A1PDE4APDE4BPDE4C
SCHEMBL9123408 0.76 PDE4A (0.52) LMNAPDE4APDE4BPDE4CPDE4D
SCHEMBL7604999 0.76 TSHR (0.33) KDM4EMEN1KMT2ALMNAPDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-7033751-A None JP disclosed
JP-H0733751-A FULLERENE DERIVATIVE AND PHOTOSENSITIVE MATERIAL NIPPON OIL CO LTD 1995-02-03 JP disclosed