Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 2/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
| ▸ | CASP1 | P29466 | 3/20 | 0.37 |
| ▸ | CASP7 | P55210 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21265816 | 0.81 | KDM4E (0.43) | PDE4APDE4BPDE4CPDE4DNPSR1 | |
| SCHEMBL6217047 | 0.78 | ADORA2B (0.38) | PDE4APDE4BPDE4CPDE4DKDM4E | |
| SCHEMBL9117929 | 0.77 | HSD17B10 (0.42) | PDE4APDE4BPDE4CPDE4DKDM4E | |
| SCHEMBL21265817 | 0.76 | PDE4A (0.41) | PDE4APDE4BPDE4CPDE4DNPSR1 | |
| SCHEMBL26940381 | 0.76 | KDM4E (0.42) | PDE4APDE4BPDE4CPDE4DKDM4E | |
| SCHEMBL7834052 | 0.75 | PDE4A (0.40) | PDE4APDE4BPDE4CPDE4DBRD4 | |
| SCHEMBL27338495 | 0.72 | ADORA2B (0.47) | PDE4APDE4BPDE4CPDE4DKDM4E | |
| SCHEMBL30555617 | 0.71 | SLC9A1 (0.46) | PDE4APDE4BPDE4CPDE4DNPSR1 | |
| SCHEMBL11435885 | 0.71 | KDM4E (0.40) | PDE4APDE4BPDE4CPDE4DNPSR1 | |
| SCHEMBL8071799 | 0.71 | TRPC5 (0.43) | PDE4APDE4BPDE4CPDE4DKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017218454-A1 | HYDROPHOBIC INTERACTION CHROMATOGRAPHY FOR PURIFICATION OF OLIGONUCLEOTIDES | BIOGEN MA INC. (US) | 2017-12-21 | — | — | WO | disclosed |