Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9118429 | 1.00 | DRD2 (0.76) | DRD2HTR1A | |
| SCHEMBL9119258 | 0.86 | HTR1A (1.00) | DRD2HTR1A | |
| SCHEMBL9119265 | 0.86 | HTR1A (1.00) | DRD2HTR1A | |
| Hydrochloric Acid SCHEMBL9441254 | 0.85 | HTR1A (0.97) | DRD2HTR1A | |
| Hydrochloric Acid SCHEMBL9120284 | 0.85 | HTR1A (0.97) | DRD2HTR1A | |
| SCHEMBL9119868 | 0.83 | HTR1A (0.77) | DRD2HTR1A | |
| SCHEMBL9119857 | 0.83 | HTR1A (0.77) | DRD2HTR1A | |
| SCHEMBL9121595 | 0.81 | DRD2 (0.72) | DRD2HTR1A | |
| Hydrochloric Acid SCHEMBL9118145 | 0.81 | DRD2 (0.72) | DRD2HTR1A | |
| Hydrochloric Acid SCHEMBL9441271 | 0.81 | DRD2 (0.72) | DRD2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0548664-B1 | 2,3,3a-5,9b-hexahydro-1H-benzo(e)indole derivatives | HOFFMANN LA ROCHE (CH) | 1995-05-31 | — | — | EP | disclosed |
| US-5318966-A | Administering the enzyme inhibitor for treating alzheimer's disease, learning enhancement, brain disorders | HOFFMANN-LA ROCHE INC. (US) | 1994-06-07 | — | — | US | disclosed |
| US-5318967-A | Cognition activators for alzheimer's disease, learning enhancement | HOFFMANN-LA ROCHE INC. (US) | 1994-06-07 | — | — | US | disclosed |
| EP-0548664-A1 | 2,3,3a-5,9b-hexahydro-1H-benzo(e)indole derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1993-06-30 | — | — | EP | disclosed |