SCHEMBL9118901

SCHEMBL9118901

C(=Cc1cccc(C=CC2=Cc3ccccc32)c1)C1=Cc2ccccc21

nearest known ligand 0.39

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
NFE2L2 Q16236 6/20 0.39
CYP19A1 P11511 2/20 0.39
MAOA P21397 1/20 0.39
MAOB P27338 1/20 0.39
NR1H3 Q13133 2/20 0.36
RELA Q04206 1/20 0.35
LCK P06239 1/20 0.35
PDK2 Q15119 1/20 0.35
FBP1 P09467 1/20 0.34
APP P05067 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5684522 0.88 MAOB (0.42) NFE2L2CYP19A1MAOAMAOBRELA
SCHEMBL5684532 0.88 MAOB (0.42) NFE2L2CYP19A1MAOAMAOBRELA
SCHEMBL9118912 0.85 CDC25B (0.34)
SCHEMBL9118904 0.85 CDC25B (0.34)
SCHEMBL9075196 0.74 MAPK1 (0.42) NFE2L2CYP19A1MAOAMAOBRELA
SCHEMBL31236759 0.74 MAPK1 (0.42) NFE2L2CYP19A1MAOAMAOBRELA
SCHEMBL29145309 0.72 CDC25A (0.31)
SCHEMBL1901796 0.70 NFE2L2 (0.68) NFE2L2CYP19A1MAOAMAOBRELA
SCHEMBL1901794 0.70 NFE2L2 (0.68) NFE2L2CYP19A1MAOAMAOBRELA
SCHEMBL3025090 0.69 MEN1 (0.39) MAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5388328-A Forming metal layer, forming resist, filling windows in resist with conductor by plating, forming another windowed resist, filling windows with conductor, dissolving resist, filling spacings with varnish, curing HITACHI, LTD. (JP) 1995-02-14 US disclosed