Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 2/20 | 0.38 |
| ▸ | TLR1 | Q15399 | 2/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 10/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9118323 | 0.83 | GABRA2 (0.41) | — | |
| SCHEMBL9119865 | 0.74 | GABRA2 (0.40) | TSHRL3MBTL1 | |
| SCHEMBL9117257 | 0.72 | TLR2 (0.38) | TLR2TLR1SCN9AALDH1A1GPR119 | |
| SCHEMBL9117236 | 0.71 | TLR2 (0.37) | TLR2TLR1SCN9AALDH1A1GPR119 | |
| SCHEMBL21317096 | 0.70 | ALKBH2 (0.47) | ALDH1A1LMNAMAPTHTTMCL1 | |
| SCHEMBL21317169 | 0.70 | MCL1 (0.45) | TLR2TLR1MRGPRX4SCN9AALDH1A1 | |
| SCHEMBL21316988 | 0.69 | MCL1 (0.46) | MRGPRX4SCN9AALDH1A1LMNAHTT | |
| SCHEMBL21317216 | 0.69 | HTT (0.43) | MRGPRX4SCN9AALDH1A1MAPTHTT | |
| SCHEMBL10478365 | 0.68 | MCL1 (0.46) | SCN9ATSHRL3MBTL1ALDH1A1MEN1 | |
| SCHEMBL21317196 | 0.68 | ALDH1A1 (0.49) | MRGPRX4SCN9AALDH1A1HTTMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0396427-B1 | Pesticidal 1-arylimidazoles | RHONE POULENC AGROCHIMIE (FR) | 1995-09-13 | — | — | EP | claimed |
| EP-0396427-A1 | Pesticidal 1-arylimidazoles | RHONE-POULENC AGROCHIMIE (FR) | 1990-11-07 | — | — | EP | claimed |