Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 7/20 | 0.57 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | ABCC1 | P33527 | 4/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.50 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.50 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.50 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9558536 | 0.90 | MAPT (0.59) | ABCB1ABCG2MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL9121209 | 0.84 | MAPK1 (0.52) | ABCB1MAPTALDH1A1SMN1; SMN2ABCC1 | |
| SCHEMBL4940856 | 0.83 | L3MBTL1 (0.68) | ABCG2MAPTALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL30819288 | 0.83 | L3MBTL1 (0.68) | ABCG2MAPTALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL9117636 | 0.83 | MAPT (0.62) | ABCG2MAPTALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL7562427 | 0.80 | ALDH1A1 (0.61) | ABCB1MAPTALDH1A1SMN1; SMN2ABCC1 | |
| SCHEMBL9119123 | 0.79 | ABCB1 (0.47) | ABCB1MAPTALDH1A1SMN1; SMN2ABCC1 | |
| SCHEMBL4216643 | 0.77 | AKR1C3 (0.58) | ABCB1MAPTALDH1A1ABCC1MAPK1 | |
| SCHEMBL359057 | 0.77 | ALDH1A1 (0.61) | ABCB1ALDH1A1ABCC1L3MBTL1TDP1 | |
| SCHEMBL30423771 | 0.77 | ALDH1A1 (0.61) | ABCB1ALDH1A1ABCC1L3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0477819-B1 | Benzimidazole derivatives, their preparation and use | NEUROSEARCH AS (DK) | 1995-03-15 | — | — | EP | disclosed |