Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 4/20 | 0.58 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.58 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.54 |
| ▸ | AKR1C4 | P17516 | 2/20 | 0.54 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.54 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ASPH | Q12797 | 1/20 | 0.52 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | CASP7 | P55210 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | MYC | P01106 | 2/20 | 0.50 |
| ▸ | MAX | P61244 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL453183 | 0.84 | AKR1C3 (0.68) | AKR1C3AKR1C2AKR1B1AKR1C4AKR1C1 | |
| SCHEMBL21248588 | 0.84 | AKR1C3 (0.58) | AKR1C3AKR1C2AKR1B1AKR1C4AKR1C1 | |
| SCHEMBL4213908 | 0.81 | AKR1C3 (0.55) | AKR1C3AKR1C2AKR1B1AKR1C4AKR1C1 | |
| SCHEMBL13877204 | 0.81 | AKR1C3 (0.55) | AKR1C3AKR1C2AKR1B1AKR1C4AKR1C1 | |
| SCHEMBL4217003 | 0.80 | AKR1C3 (0.64) | AKR1C3AKR1C2ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL5193454 | 0.79 | CRHBP (0.59) | ALDH1A1MAPK1TDP1MEN1KMT2A | |
| SCHEMBL4218109 | 0.79 | ACMSD (0.60) | AKR1C3AKR1C2AKR1B1AKR1C4AKR1C1 | |
| SCHEMBL4217337 | 0.79 | FABP3 (0.73) | AKR1C3AKR1C2AKR1B1AKR1C4AKR1C1 | |
| SCHEMBL4223100 | 0.78 | AKR1C3 (0.67) | AKR1C3AKR1C2ALDH1A1TDP1MEN1 | |
| SCHEMBL9119093 | 0.77 | ABCB1 (0.57) | AKR1C3AKR1C2AKR1B1AKR1C4AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8327467-B2 | Anthranilic acid derivative or salt thereof | TOYAMA CHEMICAL CO., LTD. (JP) | 2012-12-11 | — | — | US | disclosed |
| EP-1860098-B1 | NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO LTD (JP) | 2012-11-14 | — | — | EP | disclosed |
| US-20090105474-A1 | NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 2009-04-23 | — | — | US | disclosed |
| EP-1860098-A1 | NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 2007-11-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090105474-A1 | NOVEL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF | MMP13, MMP11, MMP3 | AKR1C3 105/4885AKR1C2 287/4885AKR1B1 305/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.