Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.53 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | NOS3 | P29474 | 1/20 | 0.43 |
| ▸ | NOS1 | P29475 | 1/20 | 0.43 |
| ▸ | NOS2 | P35228 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
| ▸ | SGMS2 | Q8NHU3 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9125515 | 0.83 | LTA4H (0.61) | LTA4HMAPK14NPC1RAB9AMAPT | |
| SCHEMBL9127242 | 0.79 | LTA4H (0.55) | LTA4HMAPK14NPC1RAB9AMAPT | |
| SCHEMBL9125591 | 0.78 | LTA4H (0.73) | LTA4HMAPK14NPC1RAB9AMAPT | |
| SCHEMBL9746554 | 0.77 | LTA4H (0.61) | LTA4HMAPK14NPC1RAB9AMAPT | |
| SCHEMBL9126648 | 0.75 | LTA4H (0.51) | LTA4HMAPK14NPC1RAB9AMAPT | |
| SCHEMBL9747086 | 0.75 | LTA4H (0.58) | LTA4HMAPK14NPC1RAB9AMAPT | |
| SCHEMBL6080009 | 0.74 | NPC1 (0.61) | LTA4HMAPK14NPC1RAB9AMAPT | |
| SCHEMBL11079744 | 0.74 | GAA (0.49) | MAPTSMN1; SMN2ALDH1A1TAAR1TACR1 | |
| SCHEMBL5644137 | 0.73 | PTGDR2 (0.45) | MAPTHTTKDM4ETAAR1TACR1 | |
| SCHEMBL10675576 | 0.72 | LTA4H (0.71) | LTA4HMAPK14NPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5459132-A | Inhibition of cell proliferation, analgesic, hypotensive | LABORATOIRES UPSA (FR) | 1995-10-17 | — | — | US | disclosed |
| WO-1995018817-A1 | NOVEL ADENOSINE DERIVATIVES, PREPARATION METHODS THEREFOR, AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LABORATOIRES UPSA (FR) | 1995-07-13 | — | — | WO | disclosed |