Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TACR1 | P25103 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10867589 | 0.83 | ALDH1A1 (0.54) | GAAALDH1A1MAPTJAK2LMNA | |
| SCHEMBL5644137 | 0.83 | PTGDR2 (0.45) | GAAMAPTLMNATAAR1L3MBTL1 | |
| SCHEMBL2557287 | 0.81 | LIPE (0.55) | GAAALDH1A1MAPTSMN1; SMN2TAAR1 | |
| SCHEMBL5838420 | 0.79 | ALDH1A1 (0.57) | ALDH1A1TP53PTGDR2KMT2A | |
| SCHEMBL23680050 | 0.77 | CDK4 (0.56) | ALDH1A1SMN1; SMN2L3MBTL1CYP19A1TSHR | |
| SCHEMBL27814043 | 0.75 | SMN1; SMN2 (0.51) | ALDH1A1MAPTLMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL8592978 | 0.74 | SMN1; SMN2 (0.54) | GAAALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL9119121 | 0.74 | LTA4H (0.53) | ALDH1A1MAPTSMN1; SMN2TAAR1L3MBTL1 | |
| SCHEMBL7545101 | 0.73 | MAPT (0.53) | GAAALDH1A1MAPTJAK2LMNA | |
| SCHEMBL5839223 | 0.73 | FABP3 (0.58) | ALDH1A1MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE31624-E | INHIBITORS OF PROSTAGLANDIN SYNTHESIS | FORSYTH DENTAL INFIRMARY FOR CHILDREN (US) | 1984-07-03 | — | — | US | claimed |
| US-4244956-A | PROSTAGLANDIN SYNTHESIS INHIBITORS | FORSYTH DENTAL INFIRMARY FOR CHILDREN (US) | 1981-01-13 | — | — | US | claimed |