Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 1/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.43 |
| ▸ | ACACB | O00763 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.38 |
| ▸ | WNT3A | P56704 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9237726 | 0.81 | ALDH1A1 (0.48) | RAB9ANPC1CTNNB1WNT3A | |
| SCHEMBL21448802 | 0.79 | PRKCI (0.57) | PRKCIMAPK14TAS1R3TAS1R1RAB9A | |
| SCHEMBL10843530 | 0.74 | PRKCI (0.58) | PRKCITAS1R3TAS1R1RAB9ANPC1 | |
| SCHEMBL9241493 | 0.74 | TAS1R3 (0.43) | PRKCIMAPK14TAS1R3TAS1R1ACACB | |
| SCHEMBL11191099 | 0.73 | TAS1R3 (0.59) | PRKCIMAPK14TAS1R3TAS1R1ACACB | |
| SCHEMBL8953567 | 0.72 | GSK3B (0.51) | RAB9ANPC1 | |
| SCHEMBL8608561 | 0.72 | TAS1R3 (0.39) | TAS1R3TAS1R1RAB9A | |
| SCHEMBL14638710 | 0.71 | PRKCI (0.51) | PRKCIMAPK14TAS1R3TAS1R1RAB9A | |
| SCHEMBL1924077 | 0.71 | PRKCI (0.54) | PRKCIMAPK14TAS1R3TAS1R1ACACB | |
| SCHEMBL11022359 | 0.70 | PRKCI (0.66) | PRKCITAS1R3TAS1R1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995025099-A1 | 2-CYANO-1,3-DIONE DERIVATIVES USEFUL AS HERBICIDES | RHONE-POULENC AGRICULTURE LTD. (GB) | 1995-09-21 | — | — | WO | claimed |
| WO-1995025099-A1 | 2-CYANO-1,3-DIONE DERIVATIVES USEFUL AS HERBICIDES | RHONE-POULENC AGRICULTURE LTD. (GB) | 1995-09-21 | — | — | WO | disclosed |