Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.49 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.49 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.49 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CTSV | O60911 | 1/20 | 0.45 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4985930 | 0.83 | PDK1 (0.51) | LTA4HMAPK1PDK1PDK2PDK3 | |
| Hydrochloric Acid SCHEMBL4984301 | 0.82 | PDK1 (0.50) | LTA4HMAPK1PDK1PDK2PDK3 | |
| SCHEMBL9118646 | 0.81 | NOX1 (0.62) | LTA4HLMNAMEN1KMT2A | |
| SCHEMBL9119429 | 0.79 | APP (0.44) | MAPK1KMT2AMAOBCYP2D6APP | |
| SCHEMBL4983985 | 0.76 | MAOB (0.54) | MAOBCYP2D6APP | |
| SCHEMBL4986647 | 0.75 | NOX1 (0.55) | LTA4HLMNAMEN1KMT2A | |
| SCHEMBL4981293 | 0.75 | NOX1 (0.52) | LTA4HMAPK1PDK1PDK2PDK3 | |
| SCHEMBL10806965 | 0.75 | PDK1 (0.61) | LTA4HPDK1PDK2PDK3PDK4 | |
| SCHEMBL4986932 | 0.74 | SIGMAR1 (0.62) | MAPK1MAOBAPP | |
| SCHEMBL5174579 | 0.74 | MAOB (0.56) | KMT2AMAOBCYP2D6APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995020950-A1 | THERAPEUTIC GUANIDINES | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1995-08-10 | — | — | WO | disclosed |