Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 5/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 2/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.41 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4986932 | 0.83 | SIGMAR1 (0.62) | APPMAOBMAPK1SIGMAR1 | |
| SCHEMBL9118652 | 0.81 | NOS3 (0.50) | MAOBKMT2A | |
| SCHEMBL9119425 | 0.79 | LTA4H (0.51) | APPMAOBCYP2D6MAPK1KMT2A | |
| SCHEMBL4983985 | 0.76 | MAOB (0.54) | APPMAOBCYP2D6BCHECYP4F2 | |
| SCHEMBL4986651 | 0.75 | SIGMAR1 (0.60) | APPSIGMAR1 | |
| SCHEMBL4985930 | 0.74 | PDK1 (0.51) | APPMAOBMAPK1KMT2A | |
| SCHEMBL5174579 | 0.74 | MAOB (0.56) | APPMAOBCYP2D6CYP4F2CYP4A11 | |
| SCHEMBL6962789 | 0.74 | APP (0.74) | APPMAOBBCHECYP4F2CYP4A11 | |
| Hydrochloric Acid SCHEMBL4984301 | 0.73 | PDK1 (0.50) | APPMAOBMAPK1KMT2A | |
| SCHEMBL7507926 | 0.73 | MAOB (0.57) | MAOBBCHECYP4F2CYP4A11MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995020950-A1 | THERAPEUTIC GUANIDINES | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1995-08-10 | — | — | WO | disclosed |