Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 5/20 | 0.39 |
| ▸ | FAAH | O00519 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9120778 | 0.91 | ALDH1A1 (0.43) | ALDH1A1MAPTKDM4ELMNACYP3A4 | |
| SCHEMBL8905009 | 0.86 | BLM (0.44) | ALDH1A1MAPTKDM4ELMNACYP3A4 | |
| SCHEMBL29449362 | 0.85 | ALDH1A1 (0.44) | ALDH1A1LMNASLC6A2CES1 | |
| SCHEMBL9119940 | 0.84 | ALDH1A1 (0.43) | ALDH1A1MAPTKDM4ELMNACYP3A4 | |
| SCHEMBL18785764 | 0.78 | ALDH1A1 (0.47) | ALDH1A1MAPTKDM4ELMNACYP3A4 | |
| SCHEMBL27868817 | 0.78 | FAAH (0.42) | ALDH1A1MAPTKDM4ELMNACYP3A4 | |
| SCHEMBL7297621 | 0.74 | ESR1 (0.47) | ALDH1A1LMNACYP3A4SLC6A2MMP13 | |
| SCHEMBL25476052 | 0.74 | ALDH1A1 (0.43) | ALDH1A1MAPTKDM4ELMNACYP3A4 | |
| Trifluoromethanesulfonic Acid SCHEMBL3362549 | 0.74 | ALDH1A1 (0.50) | ALDH1A1MAPTKDM4ELMNACYP3A4 | |
| SCHEMBL28882524 | 0.73 | ALDH1A1 (0.44) | ALDH1A1LMNASLC6A2CES1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0512953-B1 | Process for the preparation of benzene sulfonamides | CIBA GEIGY AG (CH) | 1995-06-07 | — | — | EP | disclosed |
| EP-0512953-A1 | Process for the preparation of benzene sulfonamides | CIBA-GEIGY AG (CH) | 1992-11-11 | — | — | EP | disclosed |