Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 6/20 | 0.41 |
| ▸ | FAAH | O00519 | 4/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27868817 | 0.92 | FAAH (0.42) | BLMALDH1A1KDM4ELMNACYP3A4 | |
| SCHEMBL9119441 | 0.86 | ALDH1A1 (0.42) | BLMALDH1A1KDM4ELMNACYP3A4 | |
| SCHEMBL144712 | 0.84 | ALDH1A1 (0.48) | ALDH1A1CES1FAAHTDP1NPC1 | |
| Carbamic Acid SCHEMBL26129592 | 0.81 | CES1 (0.47) | ALDH1A1LMNAGAACES1FAAH | |
| SCHEMBL18785764 | 0.81 | ALDH1A1 (0.47) | BLMALDH1A1KDM4ELMNACYP3A4 | |
| SCHEMBL9119940 | 0.80 | ALDH1A1 (0.43) | BLMALDH1A1KDM4ELMNACYP3A4 | |
| SCHEMBL11143285 | 0.80 | MAOB (0.50) | ALDH1A1CES1FAAHTDP1EPHX2 | |
| SCHEMBL9120778 | 0.76 | ALDH1A1 (0.43) | BLMALDH1A1KDM4ELMNACYP3A4 | |
| Trifluoromethanesulfonic Acid SCHEMBL3362549 | 0.76 | ALDH1A1 (0.50) | BLMALDH1A1KDM4ELMNACYP3A4 | |
| SCHEMBL11141383 | 0.76 | CALM1 (0.52) | ALDH1A1LMNACES1TDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5637763-A | Process for the preparation of substituted benzenes and benzene sulfonic acid and derivatives thereof and a process for the preparation of N,N'-substituted ureas | CIBA-GEIGY CORPORATION (US) | 1997-06-10 | — | — | US | disclosed |
| EP-0584043-B1 | Process for the preparation of substituted benzenes and benzene sulfonic acid and derivatives thereof and a process for the preparation of N'N-substituted ureas | CIBA GEIGY AG (CH) | 1996-10-30 | — | — | EP | disclosed |
| US-5508402-A | Process for the preparation of N,N'-substituted ureas | CIBA-GEIGY CORPORATION (US) | 1996-04-16 | — | — | US | disclosed |
| EP-0584043-A1 | Process for the preparation of substituted benzenes and benzene sulfonic acid and derivatives thereof and a process for the preparation of N'N-substituted ureas | CIBA-GEIGY AG (CH) | 1994-02-23 | — | — | EP | disclosed |