Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 2/20 | 0.50 |
| ▸ | CCND1 | P24385 | 2/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.45 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | HCAR1 | Q9BXC0 | 2/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29833591 | 1.00 | CDK4 (0.50) | CDK4CCND1MAPK14MAPK11ALDH1A1 | |
| SCHEMBL9052724 | 0.83 | KMT2A (0.43) | ALDH1A1KDM4EMAPTOPRM1HCAR1 | |
| SCHEMBL5973251 | 0.82 | CDK4 (0.53) | CDK4CCND1ALDH1A1KDM4EOPRM1 | |
| SCHEMBL29833592 | 0.82 | CDK4 (0.53) | CDK4CCND1ALDH1A1KDM4EOPRM1 | |
| SCHEMBL6658181 | 0.80 | ADORA3 (0.48) | ALDH1A1SMN1; SMN2MAPTHCAR1MGLL | |
| SCHEMBL10593112 | 0.78 | GUSB (0.47) | CDK4CCND1MAPK14MAPK11ALDH1A1 | |
| SCHEMBL7650490 | 0.78 | MAPK11 (0.40) | CDK4CCND1MAPK14MAPK11ALDH1A1 | |
| SCHEMBL8386511 | 0.76 | HCAR1 (0.47) | ALDH1A1KDM4EMAPTHCAR1LMNA | |
| SCHEMBL3170478 | 0.75 | MAPK1 (0.47) | ALDH1A1SMN1; SMN2KDM4ELMNAMAPK1 | |
| SCHEMBL9031575 | 0.75 | PARP1 (0.41) | CDK4CCND1MAPK14MAPK11KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117402122-A | Preparation method of sulfentrazone and triazolone-oxadiazon triazolinone intermediate | 宁夏格瑞精细化工有限公司 | 2024-01-16 | — | — | CN | disclosed |
| CN-115850195-A | Synthetic method of sulfentrazone intermediate | 宁夏格瑞精细化工有限公司 | 2023-03-28 | — | — | CN | disclosed |
| CN-113402472-B | Synthetic method of sulfentrazone intermediate | 山东潍坊润丰化工股份有限公司 | 2022-09-13 | — | — | CN | disclosed |
| CN-113402472-A | Synthetic method of sulfentrazone intermediate | 山东潍坊润丰化工股份有限公司 | 2021-09-17 | — | — | CN | disclosed |
| US-5468868-A | Process for the selective chlorination of 4,5-dihydro-1-phenyl-1H-1,2,4-triazol-5-one | FMC CORPORATION (US) | 1995-11-21 | — | — | US | disclosed |