Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 5/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.55 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | UCHL3 | P15374 | 1/20 | 0.52 |
| ▸ | GALR3 | O60755 | 1/20 | 0.45 |
| ▸ | EP300 | Q09472 | 1/20 | 0.45 |
| ▸ | PTGER4 | P35408 | 6/20 | 0.42 |
| ▸ | PTGER3 | P43115 | 5/20 | 0.42 |
| ▸ | PTGER2 | P43116 | 4/20 | 0.42 |
| ▸ | PTGER1 | P34995 | 4/20 | 0.42 |
| ▸ | PPARG | P37231 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9119838 | 1.00 | TRPA1 (0.55) | TRPA1HPGDMEN1ALDH1A1KMT2A | |
| SCHEMBL8822969 | 0.83 | TRPA1 (0.48) | TRPA1HPGDMEN1ALDH1A1KMT2A | |
| SCHEMBL2948516 | 0.83 | TRPA1 (0.61) | TRPA1HPGDMEN1ALDH1A1KMT2A | |
| SCHEMBL2948519 | 0.83 | TRPA1 (0.61) | TRPA1HPGDMEN1ALDH1A1KMT2A | |
| SCHEMBL8822983 | 0.83 | TRPA1 (0.50) | TRPA1HPGDMEN1ALDH1A1KMT2A | |
| SCHEMBL8822989 | 0.83 | TRPA1 (0.50) | TRPA1HPGDMEN1ALDH1A1KMT2A | |
| SCHEMBL8822884 | 0.79 | PTGER2 (0.47) | TRPA1HPGDMEN1ALDH1A1KMT2A | |
| SCHEMBL8822883 | 0.79 | PTGER2 (0.47) | TRPA1HPGDMEN1ALDH1A1KMT2A | |
| SCHEMBL19732190 | 0.77 | TRPA1 (0.64) | TRPA1HPGDMEN1ALDH1A1KMT2A | |
| SCHEMBL21631706 | 0.77 | TRPA1 (0.59) | TRPA1HPGDMEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0444844-B1 | New 15-dehydroxy-16-oxoprostaglandins | R TECH UENO LTD (JP) | 1995-01-18 | — | — | EP | disclosed |
| US-5221799-A | New 15-dehydroxy-16-oxoprostaglandins | K.K. UENO SEIYAKU OYO KENKYUJO (JP) | 1993-06-22 | — | — | US | disclosed |
| EP-0444844-A2 | New 15-dehydroxy-16-oxoprostaglandins | R-TECH UENO LTD. (JP) | 1991-09-04 | — | — | EP | disclosed |