Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | HPGD | P15428 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.61 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | UCHL3 | P15374 | 1/20 | 0.57 |
| ▸ | PPARG | P37231 | 5/20 | 0.53 |
| ▸ | RECQL | P46063 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | MIF | P14174 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | GALR3 | O60755 | 1/20 | 0.52 |
| ▸ | EP300 | Q09472 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2948519 | 1.00 | TRPA1 (0.61) | TRPA1MEN1ALDH1A1KMT2AHPGD | |
| SCHEMBL19732190 | 0.90 | TRPA1 (0.64) | TRPA1MEN1ALDH1A1KMT2AHPGD | |
| SCHEMBL21631706 | 0.90 | TRPA1 (0.59) | TRPA1MEN1ALDH1A1KMT2AHPGD | |
| SCHEMBL30209147 | 0.90 | TRPA1 (0.59) | TRPA1MEN1ALDH1A1KMT2AHPGD | |
| SCHEMBL2948236 | 0.87 | PTGER4 (0.48) | TRPA1MEN1ALDH1A1KMT2AHPGD | |
| SCHEMBL2948238 | 0.87 | PTGER4 (0.48) | TRPA1MEN1ALDH1A1KMT2AHPGD | |
| SCHEMBL8822989 | 0.86 | TRPA1 (0.50) | TRPA1MEN1ALDH1A1KMT2AHPGD | |
| SCHEMBL8822983 | 0.86 | TRPA1 (0.50) | TRPA1MEN1ALDH1A1KMT2AHPGD | |
| SCHEMBL14538124 | 0.84 | PPARG (0.49) | TRPA1MEN1ALDH1A1KMT2AHPGD | |
| SCHEMBL594566 | 0.84 | PPARG (0.49) | TRPA1MEN1ALDH1A1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7759399-B2 | Pharmaceutical compositions | CRAWFORD HEALTHCARE HOLDINGS LIMITED (GB) | 2010-07-20 | — | — | US | disclosed |
| US-20060252839-A1 | Pharmaceutical compositions | BIOGEM S.C.A.R.L. (IT) | 2006-11-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060252839-A1 | Pharmaceutical compositions | ADK, SYMPK, CYP2J2 | TRPA1 1929/4885MEN1 3916/4885ALDH1A1 981/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.