Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | SNCA | P37840 | 1/20 | 0.38 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.38 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL647364 | 0.88 | ALDH1A1 (0.40) | ALDH1A1TDP1GAACYP1A2KDM4E | |
| SCHEMBL646209 | 0.79 | GAA (0.44) | ALDH1A1TDP1TAS1R3TAS1R1GAA | |
| SCHEMBL645502 | 0.69 | MEN1 (0.38) | ALDH1A1GAACYP1A2KDM4EHTT | |
| SCHEMBL9440575 | 0.68 | POLB (0.38) | ALDH1A1GAACYP1A2KDM4EHTT | |
| SCHEMBL20335193 | 0.67 | ALDH1A1 (0.44) | ALDH1A1TDP1GAACYP1A2KDM4E | |
| SCHEMBL16160025 | 0.67 | GAA (0.67) | ALDH1A1TDP1GAACYP1A2KDM4E | |
| SCHEMBL9440652 | 0.67 | MEN1 (0.40) | ALDH1A1TDP1GAACYP1A2KDM4E | |
| SCHEMBL6675235 | 0.67 | POLB (0.36) | ALDH1A1GAAKDM4EHTTHPGD | |
| SCHEMBL23761193 | 0.66 | GAA (0.65) | ALDH1A1TDP1GAACYP1A2KDM4E | |
| SCHEMBL7813363 | 0.66 | GAA (0.75) | ALDH1A1TDP1GAACYP1A2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0350314-B1 | Silicone type cinnamic acid derivative, preparation method thereof, uv-ray absorber, and external skin treatment agent. | SHISEIDO CO LTD (JP) | 1995-12-13 | — | — | EP | disclosed |
| US-5315022-A | Sunscreen | SHISEIDO COMPANY LTD. (JP) | 1994-05-24 | — | — | US | disclosed |
| US-5093511-A | SILICONE TYPE CINNAMIC ACID DERIVATIVE, PREPARATION METHOD THEREOF, UV-RAY ABSORBER, AND EXTERNAL SKIN TREATMENT AGENT | SHISEIDO COMPANY, LTD. (JP) | 1992-03-03 | — | — | US | disclosed |