Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | CFTR | P13569 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.39 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SORT1 | Q99523 | 3/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9183496 | 0.82 | MAPT (0.51) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL9118243 | 0.80 | L3MBTL1 (0.64) | ALDH1A1KDM4EHPGDHSD17B10L3MBTL1 | |
| SCHEMBL5539791 | 0.77 | L3MBTL1 (0.56) | ALDH1A1KDM4EHPGDHSD17B10L3MBTL1 | |
| SCHEMBL8075204 | 0.75 | KDM4E (0.47) | ALDH1A1KDM4EHPGDHSD17B10L3MBTL1 | |
| SCHEMBL3833670 | 0.75 | KDM4E (0.59) | ALDH1A1KDM4EHPGDHSD17B10L3MBTL1 | |
| SCHEMBL345774 | 0.74 | KDM4E (0.58) | ALDH1A1KDM4EHPGDHSD17B10CFTR | |
| SCHEMBL422034 | 0.74 | ALDH1A1 (0.71) | ALDH1A1KDM4EHPGDHSD17B10RAB9A | |
| SCHEMBL9188388 | 0.74 | KDM4E (0.46) | ALDH1A1KDM4EHPGDHSD17B10L3MBTL1 | |
| SCHEMBL330883 | 0.74 | L3MBTL1 (0.70) | ALDH1A1KDM4EHPGDHSD17B10L3MBTL1 | |
| Hydrochloric Acid SCHEMBL10978991 | 0.73 | KDM4E (0.56) | ALDH1A1KDM4EHPGDHSD17B10CFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995033460-A1 | ANTI-INFLAMMATORY COUMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1995-12-14 | — | — | WO | disclosed |
| US-5447957-A | Anti-inflammatory compounds | SMITHKLINE BEECHAM CORP. (US) | 1995-09-05 | — | — | US | disclosed |