SCHEMBL91202

SCHEMBL91202

C=Cc1cccc(Br)c1O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.45
GAA P10253 4/20 0.45
LMNA P02545 2/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
RAB9A P51151 3/20 0.39
KDM4E B2RXH2 2/20 0.39
NPC1 O15118 2/20 0.39
MAPK1 P28482 1/20 0.39
GFER P55789 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
ALDH1A1 P00352 1/20 0.38
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA9 Q16790 1/20 0.38
HSD11B1 P28845 1/20 0.36
ERN1 O75460 4/20 0.35
KMT2A Q03164 4/20 0.35
MEN1 O00255 3/20 0.35
HTT P42858 1/20 0.35
POLB P06746 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4962062 0.83 ALDH1A1 (0.46) MAPTGAALMNARAB9AKDM4E
SCHEMBL91201 0.77 ERN1 (0.61) MAPTGAALMNASMN1; SMN2RAB9A
SCHEMBL29356117 0.76 ERN1 (0.60) MAPTGAALMNASMN1; SMN2RAB9A
SCHEMBL131222 0.76 ERN1 (0.60) MAPTGAALMNASMN1; SMN2RAB9A
SCHEMBL180459 0.76 ALDH1A1 (0.41) ALDH1A1HSD11B1
SCHEMBL29661897 0.76 ALDH1A1 (0.41) ALDH1A1HSD11B1
SCHEMBL29418131 0.75
SCHEMBL50072 0.75
SCHEMBL8010113 0.74 ALDH1A1 (0.39) RAB9ANPC1TDP1ALDH1A1HSD11B1
SCHEMBL5257067 0.74 ALDH1A1 (0.39) MAPTGAALMNASMN1; SMN2RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111032714-B Curable petroleum resin, process for its preparation and its use 可隆工业株式会社 2023-02-17 CN claimed
CN-111032714-A Curable petroleum resin, process for its preparation and its use 可隆工业株式会社 2020-04-17 CN claimed
EP-0298733-A1 Flame-retardant resin composition and laminate manufactured therefrom HITACHI, LTD. (JP) 1989-01-11 EP claimed
CN-111032714-B Curable petroleum resin, process for its preparation and its use 可隆工业株式会社 2023-02-17 CN disclosed
CN-111032714-A Curable petroleum resin, process for its preparation and its use 可隆工业株式会社 2020-04-17 CN disclosed
US-10258602-B2 Macrocyclic ghrelin receptor modulators and methods of using the same OCERA THERAPEUTICS, INC. (US) 2019-04-16 US disclosed
US-20180110824-A1 Macrocyclic Modulators of the Ghrelin Receptor OCERA THERAPEUTICS, INC. 2018-04-26 US disclosed
US-20180110824-A1 Macrocyclic Modulators of the Ghrelin Receptor OCERA THERAPEUTICS, INC. 2018-04-26 US disclosed
US-9949949-B2 Macrocyclic ghrelin receptor modulators and methods of using the same OCERA THERAPEUTICS, INC. (US) 2018-04-24 US disclosed
US-9949949-B2 Macrocyclic ghrelin receptor modulators and methods of using the same OCERA THERAPEUTICS, INC. (US) 2018-04-24 US disclosed
EP-2457893-B1 Intermediates for macrocyclic modulators of the ghrelin receptor OCERA THERAPEUTICS INC (US) 2017-08-16 EP disclosed
EP-0954966-B1 Polymeric controlled release compositions ROHM & HAAS (US) 2003-06-25 EP disclosed
EP-0954966-A1 Polymeric controlled release compositions ROHM AND HAAS COMPANY (US) 1999-11-10 EP disclosed
US-5200454-A Blend of syndiotactic polymer, thermoplastic resin, halogenated polystyrenes and phosphine oxide IDEMITSU KOSAN COMPANY LIMITED (JP) 1993-04-06 US disclosed
EP-0150772-B1 RELEASE SHEET OJI PAPER COMPANY LIMITED (JP) 1989-07-12 EP disclosed
US-4609589-A UNDERCOATINGS, ACRYLIC EMULSION, OXIDIZED STARCHES, LAMINATION, METAL FOIL, CROSSLINKING, THERMOSETTING RESINS OJI PAPER COMPANY, LTD. (JP) 1986-09-02 US disclosed
EP-0150772-A2 Release sheet OJI PAPER COMPANY LIMITED (JP) 1985-08-07 EP disclosed
US-4347305-A NONSILVER PHOTOGRAPHIC COATING OVER SILVER NALIDE EMULSION; POSITIVES; PHOTORESISTS; MASKING; FUJI PHOTO FILM CO., LTD. (JP) 1982-08-31 US disclosed
US-4268609-A Process for preparing photosensitive lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 1981-05-19 US disclosed
US-4115128-A Positive image forming radiation sensitive compositions containing diazide compound and organic cyclic anhydride FUJI PHOTO FILM CO., LTD. (JP) 1978-09-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180110824-A1 Macrocyclic Modulators of the Ghrelin Receptor GHSR, GIPR, GHRHR MAPT 4693/4885GAA 1223/4885LMNA 3873/4885
US-10258602-B2 Macrocyclic ghrelin receptor modulators and methods of using the same GHSR, GHRHR, GIPR MAPT 4766/4885GAA 1016/4885LMNA 3492/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.