Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | BAZ1A | Q9NRL2 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | STAT1 | P42224 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 2/20 | 0.41 |
| ▸ | MMP2 | P08253 | 2/20 | 0.41 |
| ▸ | MMP9 | P14780 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9124272 | 0.85 | ALDH1A1 (0.55) | SMN1; SMN2LMNAMAPTHTTPOLB | |
| SCHEMBL9127793 | 0.85 | MAPT (0.52) | SMN1; SMN2LMNARAB9AMAPTHTT | |
| SCHEMBL9123962 | 0.85 | SMN1; SMN2 (0.56) | ESR1ESR2SMN1; SMN2HPGDNPC1 | |
| SCHEMBL9125272 | 0.82 | RAB9A (0.53) | SMN1; SMN2HPGDNPC1LMNARAB9A | |
| SCHEMBL9125324 | 0.82 | KMT2A (0.46) | ESR1ESR2SMN1; SMN2BAZ1ANPC1 | |
| SCHEMBL9123643 | 0.82 | ATM (0.41) | ESR1ESR2BAZ1A | |
| SCHEMBL9122245 | 0.82 | MAPT (0.46) | ESR1ESR2SMN1; SMN2NPC1LMNA | |
| SCHEMBL9124208 | 0.81 | ATM (0.46) | ESR1ESR2SMN1; SMN2BAZ1ANPC1 | |
| SCHEMBL9127139 | 0.81 | SMN1; SMN2 (0.40) | SMN1; SMN2BAZ1AHPGDNPC1LMNA | |
| SCHEMBL9128959 | 0.81 | MMP1 (0.40) | ESR1ESR2BAZ1AMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0524419-B1 | Heat-sensitive recording materials and phenol compounds | MITSUI TOATSU CHEMICALS (JP) | 1995-09-06 | — | — | EP | disclosed |
| US-5391806-A | A storage stable chromogens as color-developing agent or stabilizers | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1995-02-21 | — | — | US | disclosed |
| US-5270281-A | Chromogenic compound | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1993-12-14 | — | — | US | disclosed |
| EP-0524419-A1 | Heat-sensitive recording materials and phenol compounds | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1993-01-27 | — | — | EP | disclosed |